DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32249 and ZNF512B

DIOPT Version :9

Sequence 1:	NP_729001.2	Gene:	CG32249 / 317939	FlyBaseID:	FBgn0052249	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	XP_024307718.1	Gene:	ZNF512B / 57473	HGNCID:	29212	Length:	1084	Species:	Homo sapiens

Alignment Length:	219	Identity:	54/219 - (24%)
Similarity:	98/219 - (44%)	Gaps:	69/219 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 VPVYRPSPV---VQIARPAPQVISVAAPRNTYLP-----PQVISRPAPQVVSIARPAPQVVSIAR 121
            :|..:|.|:   |.|:||    :.|:.|.....|     |..:|:|    :.|::|    ||:.|
Human   182 LPASKPGPISRPVTISRP----VGVSKPIGVSKPVTIGKPVGVSKP----IGISKP----VSVGR 234

  Fly   122 PAP--QVVSIARPAP--QVVSIARPAPQVVSIARPAPEVVSIARPAPEVVSIARPAP-------- 174
            |.|  :.:.:.||.|  :.|:::||.|  |:.|.|..:.:::.:..|    :.:|.|
Human   235 PMPVTKAIPVTRPVPVTKPVTVSRPMP--VTKAMPVTKPITVTKSVP----VTKPVPVTKPITVT 293

  Fly   175 QVVSIARPAP--QVVSIARP--APQVVSIVRPAPQVVSIARPAPQVISV-------AAPRNT--- 225
            ::|::.:|.|  :.|:::||  ..:.|::.||    ::|:|..|....|       .|||.|
Human   294 KLVTVTKPVPVTKPVTVSRPIVVSKPVTVSRP----IAISRHTPPCKMVLLTRSENKAPRATGRN 354

  Fly   226 -------------YLPPQVIAPRN 236
                         .:||:...|.|
Human   355 SGKKRAADSLDTCPIPPKQARPEN 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32249	NP_729001.2	PRK07994	<101..>215	CDD:236138	32/129 (25%)
ZNF512B	XP_024307718.1	DNA_pol3_gamma3	<237..462	CDD:331207	35/152 (23%)
		C2H2 Zn finger	610..631	CDD:275368
		C2H2 Zn finger	646..667	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S11813
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950