DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32246 and Ndc1

DIOPT Version :9

Sequence 1:	NP_729020.2	Gene:	CG32246 / 317936	FlyBaseID:	FBgn0052246	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_651191.1	Gene:	Ndc1 / 42825	FlyBaseID:	FBgn0039125	Length:	578	Species:	Drosophila melanogaster

Alignment Length:	600	Identity:	127/600 - (21%)
Similarity:	244/600 - (40%)	Gaps:	123/600 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KKILLYRFLFATLLCSWLDYQMLTIFVAINLFEVMRPLVSVTEILR----WTLFSVYSSVLMLLI 78
            |.:||.|.|.|.||...:.:.:||:|:....|:::.||..||..||    |  ::.::|:.::
  Fly    11 KLLLLGRCLRAVLLSVAIQFLLLTVFLLFVNFQLLHPLAWVTGTLRLVASW--YTWFASIPLV-- 71

  Fly    79 RVSTMGFGLVLCHIHYNNPRCFKNNILRITYEFPIRLGLIASILSITMTTSWLYASFV--DLNNG 141
             .|.:.:|::||..|.:..|........:.:..|.::..:.:.|.:.:.|:|||..::  |..:.
  Fly    72 -ASVVLYGVILCQQHLSERRYCPTRYRWLLHYGPRKVLFLFAHLLVGLLTAWLYTGYLHTDYQHL 135

  Fly   142 NYLLGG----SWY--YL----MTFGCFCGISYYHKSQGRCLRRFPLPIVHLDIKKCLLQMWCHQL 196
            .|...|    |.|  ||    ||.||:..:|.:.:.:    .....|||.....:.:.::....|
  Fly   136 KYKCYGQDCISAYNVYLLGIGMTAGCYYFVSVHMRKE----ISIEFPIVEQSRAEKMRELLYASL 196

  Fly   197 KTSAKAAIVPTLLFTVIY-------WPTMGFLDTTELGGVTIGCCVIITQPQRLFQAWLLATLIL 254
            ..|..::::||:.:|.::       ...:..:.:.::.....|...::|..:.||..:||...||
  Fly   197 AKSLLSSLLPTISYTAVFCLFGPMVCHRLSHILSVDMDERLDGFFGVVTNVRLLFYGYLLTAQIL 261

  Fly   255 FKLNIVPKFYGLVLQRKLSLICDLRALHKCTGINLFNLIWDRFQYFFCTMRMKPMPKDMQRYTFS 319
            ..::::..|||::|...|.|:.                               ..|:....:...
  Fly   262 SNMHLMRCFYGILLSEDLPLVV-------------------------------TKPRAAFAHEQD 295

  Fly   320 IPVAMALDTTEIYGFQLLAARDFY---AAMSGSLYLDLFKMEIGLGNR--NWRELRDIILEMVDA 379
            |.:...|....:|..|.|||..||   ...:.....::|:: ...|||  :||.|.|..|.::.:
  Fly   296 ITLVAGLGVFNVYVVQCLAAHHFYKLALRKNSPQRAEIFQL-TEPGNRPASWRSLCDQCLSILGS 359

  Fly   380 FLARMDSCLEPATPIKICHLLKNNKPKCPQ---------------------IRLLVKPTPPPKRF 423
            |...:...::..:.:|....|.  .||..:                     ||.:|.|:   :..
  Fly   360 FTEELTESMQKISILKCAQSLP--MPKITESLTTSLMAEKVLLRQYNQKHGIRPIVSPS---REV 419

  Fly   424 CVHSIRKGL-----WF----------------RLP-IVSQYYSYLYDLDPLANLNHVLLCGEPLV 466
            .|.|...|:     |.                |:| ||     ||::....|....:|....|:|
  Fly   420 AVESPADGIRHFPNWCERVSTQLEQSLQRLLQRVPGIV-----YLFNEPEGAKTTFLLANSLPVV 479

  Fly   467 WILQGLVSICVRLFKEDKFVYIESDVDRILVYLLKVEEKLNEAKEMKVRGKLCSSHDRFMK-AIN 530
            ::.|.|..:|....|||.:..:::|:..|:..:.|:..:|::...:....::.||....:: |:.
  Fly   480 YMTQALAQVCAASLKEDPYGVVQNDLPAIIKAINKLRNELDKLSSVIGNIRISSSSFNVLRCAVR 544

  Fly   531 RCLYKMLFTFSPYMD 545
            |.||.:..:|..|:|
  Fly   545 RSLYAICLSFCDYLD 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32246	NP_729020.2	None
Ndc1	NP_651191.1	Ndc1_Nup	63..571	CDD:286600	107/545 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4358
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556184at2759
OrthoFinder	1	1.000	-	-		FOG0006443
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.820