Protein Alignment t-Grip128 and Grip91

DIOPT Version :10

• Sequence 1: NP_729045.1
• Gene: t-Grip128 / 317930
• FlyBaseID: FBgn0052232
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Alignment Length: 1065
• Identity: 188/1065 - (17%)
• Similarity: 327/1065 - (30%)
• Gaps: 396/1065 - (37%)

  Fly    79 RIENLSVFGDTFNQLANVILNHPICMNHKQR-NIHWRLLDF---VLSVNYKTFVSIRRN--LPEM 137
            ||..:.|..:: ..::|:|....||:..||. .:|.:.:|.   :::.|.:.   ||.:  |.|.
  Fly     5 RIAGIDVATNS-TDISNIINEMIICIKGKQMPEVHEKAMDHLSKMIAANSRV---IRDSNMLTER 65

  Fly   138 E--QKRKNILEALQMATESSQVDPKDKNN--------TKCVADTEDQLI-HKKSQKPKSPRKKLT 191
            |  ||...:|.|.....|...|  .|..|        |||.......|: |..:....|..:|..
  Fly    66 ECVQKIMKLLSARNKKEEGKTV--SDHFNELYRKLTLTKCDPHMRHSLMTHLLTMTDNSDAEKAV 128

  Fly   192 PDQIQRL-CDEIRDLTSSKYGSLHTVRSQIPMEQSKPLDTSDYNYSRELN--------------- 240
            ..:..|. ||.:..:..|:   |:::.|.|          :..|....:|
  Fly   129 ASEDPRTQCDNLTQILVSR---LNSISSSI----------ASLNEMGVVNGNGVGAAAVTGAAAV 180

  Fly   241 LGKVAVKENFTIKGAKMELELNVVQNKPSAEKPALVDF--------------------------- 278
            .|..||.....:.||......:..|:.....|.:|.::
  Fly   181 TGAAAVTGAAAVTGAAASHSYDATQSSIGLRKQSLPNYLDATKMLPESRHDIVMSAIYSFTGVQG 245

  Fly   279 -----------FK-----------NESDMLYRIQTNWWQVDISVYNQAHILASNFCQGYADILIF 321
                       ||           .::.||.|:.      ::..|:...:..|:...|:..|...
  Fly   246 KYLKKDVVTGRFKLDQQNIKFLTTGQAGMLLRLS------ELGYYHDRVVKFSDVSTGFNAIGSM 304

  Fly   322 QLWESQASIRKLSEE----H----QLLSELIVLFFASANCRSFKILNDNWEFRADEPLTCALKQL 378
                .||.|.||.||    |    .|..|:.....||.|..:.|...|:.....||.....|
  Fly   305 ----GQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKL--- 362

  Fly   379 QEGPHLGEIIKSLKQMRHLRELIETYAVKGIRYDRLKTLTFFSVALRQLLRPVIEFLVHFERRLT 443
                 |...||.|.:|:.|.::.:...||
  Fly   363 -----LAWYIKPLHRMQWLTKIADACQVK------------------------------------ 386

  Fly   444 SGLEPATLQHFIETSRGHLETIKLLYELSQNKNQELHSLRSLKTLDTLFTKSSQKTQPKLLRSLS 508
                          ..|.|.:  .:|:...|.|..::                     ||:..|.
  Fly   387 --------------KGGDLAS--TVYDFLDNGNDMVN---------------------KLVEDLL 414

  Fly   509 ASLLLHTVRAYCKFLDNWWSTGDFADYHEEFPFEKIVTDE----------RTEYVLRKSLMQTEL 563
            .::....||    .:..|...|..:|.|.|| |.|.:.|.          |....:....:..::
  Fly   415 TAICGPLVR----MISKWILEGGISDMHREF-FVKSIKDVGVDRLWHDKFRLRLPMLPKFVPMDM 474

  Fly   564 QNSEL--------FRII--QRHLLESSDGVAILYDSRTISEFHTLHGIEPEIRLHNSLIDAVIGE 618
            .|..|        .|.|  ::.:::..|.:..:.:|.....|    ...|:...|.::...
  Fly   475 ANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIF----SYTPDTSWHAAVETC---- 531

  Fly   619 IAPYQIKAIEASHYVPDIL---QQLQSTDH-DGIRRL-------FYSFHMETRPDPRKPAGHSIN 672
               ||    :.|.:|.||:   .:|  .|| .|:||.       |.|..:|...          |
  Fly   532 ---YQ----QTSKHVLDIMVGPHKL--LDHLHGMRRYLLLGQGDFISILIENMK----------N 577

  Fly   673 ELLRNFLTCADYTPITEIISQEFQRLLNRRTRLVNSYISGLLQEFQGYKVVRHLRSVF------- 730
            ||.|         |..:|.:.:...:|:...|..|:       ::....::.||..:.
  Fly   578 ELER---------PGLDIYANDLTSMLDSALRCTNA-------QYDDPDILNHLDVIVQRPFNGD 626

  Fly   731 LLWNYDHFRSEFEFFFEFLRRKHLV--------EATNKLKHIVLCQDFTLGHMFKVCVTEAHPEF 787
            :.||             .:..:::|        |:|..          |...:||......|.||
  Fly   627 IGWN-------------IISLQYIVHGPLAAMLESTMP----------TYKVLFKPLWRMKHMEF 668

  Fly   788 ICLRVRNDTLLNRIISQQQMDMMNSCFRLLLNLNFSHYRLN-------HLPPFHYCKYERLFKAL 845
            :         |:..|.::||....:...:...:..:.:|||       |.  .|..:|..||:.:
  Fly   669 V---------LSMKIWKEQMGNAKALRTMKSEIGKASHRLNLFTSEIMHF--IHQMQYYVLFEVI 722

  Fly   846 -------------------------RSIQISLISVF---EEHLSHPCK-LFRKMQNLDSYNS--- 878
                                     :.:|..|:..|   :..:.|..: ::..:..|:.:.|
  Fly   723 ECNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFVSNKASVEHSLEVVYENIIELEKWQSSFY 787

  Fly   879 -----ELN---EFTSLTQLRRNQEIFGLHIRKYLLEEQFACSLPEILTLSKVFCLRWETT----R 931
                 |||   |.:.:.:....:.::||..:..|..:|.|          |:|..:.:..    .
  Fly   788 KDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEA----------KIFAEKMDIACRGLE 842

  Fly   932 ALVDEYRSQKATSTFERRYKLLRLN 956
            .:..:|  :||.|||     |:.||
  Fly   843 VIATDY--EKAVSTF-----LMSLN 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip128	NP_729045.1	GCP5_NTD	10..121	CDD:454848	11/45 (24%)
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	70/424 (17%)
		GCP_C_terminal	549..880	CDD:461187	69/391 (18%)