Protein Alignment CG32221 and Fbxl7

DIOPT Version :10

• Sequence 1: NP_730456.2
• Gene: CG32221 / 317924
• FlyBaseID: FBgn0052221
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_795933.2
• Gene: Fbxl7 / 448987
• MGIID: 3052506
• Length: 491
• Species: Mus musculus
• Alignment Length: 392
• Identity: 100/392 - (25%)
• Similarity: 144/392 - (36%)
• Gaps: 101/392 - (25%)

  Fly     6 SILDLDPSSLLFIFKLLSLEDQLHLARCCRIFRDAF-----LRLHRHDFQDVVDKDMSIRTLEDW 65
            ||..|...|::.||..|...   .|.||.|:.|..:     .||                    |
Mouse   113 SIDRLPDHSMVQIFSFLPTN---QLCRCARVCRRWYNLAWDPRL--------------------W 154

  Fly    66 RTFLWLCGSRIG------TLESHFDDDHP---LQLLPMISRHCYRLKSISIYNATVARAQPYLLR 121
            || :.|.|..|.      .|......|.|   |.|..:|...|.||....:|  |:|:..|.|.|
Mouse   155 RT-IRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLY--TIAQCCPELRR 216

  Fly   122 MS--------------------SLEKVHVRNYKSTSKDLIKAIGIHLPRVNSLSLESFERKELQE 166
            :.                    :||.:.|....       |...|.|.|..|:.|.....|:: .
Mouse   217 LEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCS-------KVTCISLTREASIKLSPLHGKQI-S 273

  Fly   167 VRQFSEMLELGLYDDVTASEFATIVKPMRKLRCLQLRNAKRFLTTSNLRMLATNCRHLEKLTFND 231
            :| :.:|.:..:.:|   ....||.....:|..|.||...| ||...||.|...|..:::|:.:|
Mouse   274 IR-YLDMTDCFVLED---EGLHTIAAHCTQLTHLYLRRCVR-LTDEGLRYLVIYCTSIKELSVSD 333

  Fly   232 CDADLLVLPQFVNLKYLQLYCSEDMKTRLFKALAKSQCSIQLEYL-ILHRKRWID---EEQAQYI 292
            |        :||:          |...|   .:||.:.  :|.|| |.|..|..|   ...|:|.
Mouse   334 C--------RFVS----------DFGLR---EIAKLES--RLRYLSIAHCGRITDVGIRYVAKYC 375

  Fly   293 SALKCLRWLVCKPRDDLCVHHLAK-LSRLECLSIQSAREIGETQLSLLVANNERLRYLNICYCLG 356
            |.|:.|....|:...|..|.:||| .::|:.|.|.....:.:|.|..|..|...|:.|::..|..
Mouse   376 SKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLALNCFNLKRLSLKSCES 440

  Fly   357 IT 358
            ||
Mouse   441 IT 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32221	NP_730456.2	leucine-rich repeat	197..223	CDD:275381	11/25 (44%)
		leucine-rich repeat	224..244	CDD:275381	4/19 (21%)
		leucine-rich repeat	245..272	CDD:275381	4/26 (15%)
		leucine-rich repeat	273..297	CDD:275381	11/27 (41%)
		leucine-rich repeat	298..319	CDD:275381	7/21 (33%)
		leucine-rich repeat	320..345	CDD:275381	7/24 (29%)
		leucine-rich repeat	346..372	CDD:275381	5/13 (38%)
Fbxl7	NP_795933.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..79
		F-box_FBXL7	114..157	CDD:438892	16/66 (24%)
		leucine-rich repeat	129..151	CDD:275381	6/24 (25%)
		leucine-rich repeat	154..187	CDD:275381	9/33 (27%)
		AMN1	<185..366	CDD:187754	53/218 (24%)
		LRR 1	185..210		9/26 (35%)
		leucine-rich repeat	188..213	CDD:275381	8/26 (31%)
		LRR 2	211..236		3/24 (13%)
		leucine-rich repeat	214..234	CDD:275381	2/19 (11%)
		LRR 3	237..262		7/31 (23%)
		leucine-rich repeat	240..273	CDD:275381	10/40 (25%)
		LRR 4	271..296		5/29 (17%)
		leucine-rich repeat	274..299	CDD:275381	5/28 (18%)
		AMN1	297..464	CDD:187754	50/170 (29%)
		LRR 5	297..322		10/25 (40%)
		leucine-rich repeat	300..325	CDD:275381	11/25 (44%)
		LRR 6	323..348		9/45 (20%)
		leucine-rich repeat	326..351	CDD:275381	9/47 (19%)
		LRR 7	349..374		8/26 (31%)
		leucine-rich repeat	352..377	CDD:275381	9/24 (38%)
		LRR 8	375..400		8/24 (33%)
		leucine-rich repeat	378..403	CDD:275381	8/24 (33%)
		LRR 9	401..426		6/24 (25%)
		leucine-rich repeat	404..429	CDD:275381	7/24 (29%)
		LRR 10	427..452		5/16 (31%)
		leucine-rich repeat	430..453	CDD:275381	5/13 (38%)
		leucine-rich repeat	456..480	CDD:275381