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Protein Alignment Nrg and lifrb

DIOPT Version :9

Sequence 1:	NP_001245581.1	Gene:	Nrg / 31792	FlyBaseID:	FBgn0264975	Length:	1309	Species:	Drosophila melanogaster
Sequence 2:	XP_009293599.1	Gene:	lifrb / 565104	ZFINID:	ZDB-GENE-080107-2	Length:	960	Species:	Danio rerio

Alignment Length:	1066	Identity:	195/1066 - (18%)
Similarity:	318/1066 - (29%)	Gaps:	391/1066 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 VRKAELNAFKDEAAKTLEAVEGEPFMLKCAAPDGFPSPTVNWMIQ----ESIDGSIKSINNSRMT 187
            :|..:::..|.|.:|                 ||.....|.|..:    |.:...|:.|:..:|.
Zfish    26 IRDVKVSEEKTETSK-----------------DGAWVLNVEWTDENNEFEKVSYDIEIIHTEQMR 73

  Fly   188 LDPEGNLWFSNV-TREDASSDFYY--------ACSATSV---FRSEYKIG--NKVLLDVKQMGVS 238
                 .:.|.|: .:.|.||.:::        .|::.||   .|.:.:|.  ...|....|...|
Zfish    74 -----TVHFENIHVKADKSSHYHWKWTSPIPLQCTSHSVRLRRRDQLRISEWTSYLTYTGQDQNS 133

  Fly   239 ASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQTVWSKDGQRIQWSDRITQGHYGKSLV 303
            .:...:|        |..:.|.|..:...||...........||...||.....||:.|
Zfish   134 LTSQVYP--------RNQVFLIGSNITFCCILKTEKASLNNLSKFVIRISNRTYITETH------ 184

  Fly   304 IRQTNFDDAGTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEP 368
              :..|.....|..||...|.|.:|.|     .:..:|...|      :|:.:.  |....:...
Zfish   185 --KDPFSRTSEYFSDVDCEVKNEKSSS-----GASVFFGYPP------DDQNLT--CITRDLSSV 234

  Fly   369 KISW----------------IHNGKPIEQSTPNP---RRTVTDNTIRIINLVKGDTGNYGCNATN 414
            :..|                ..||:..|.:..:|   ::.:|:.|:...|.:       |.....
Zfish   235 ECQWKLGRKTQLYGTRATNYTLNGRKCEFNRCDPLELKKQITNWTLIARNAL-------GVKIVT 292

  Fly   415 SLGYVYKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGRY-- 477
            ..|.....|:|..   |..||.|..|      ||.|            |.|    :| :...|
Zfish   293 DTGDPTHRVWLKA---PHNISHAAHA------RNAT------------VHW----SW-SVTEYAS 331

  Fly   478 -----NVQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVKEH----TRITQEPQNYEVA 533
                 .|..||:  |.:.|||..|.                :.||.||    |:.|.     :|:
Zfish   332 LLMICQVMLNGN--IYNKTFSGKGL----------------ASVVLEHLQPFTKYTA-----KVS 373

  Fly   534 AGQSATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVART 598
            .|         :|:...:     |.|...|.|..:
Zfish   374 CG---------SHEHFFQ-----WGDWSEITFTTK------------------------------ 394

  Fly   599 RLDEATARANLIVQDVPNAPKLTGITCQADKAEIHWEQQGDNRS-----PILH---------YTI 649
                         :|:   |:|..:          |.|..:|.:     |:.|         |.:
Zfish   395 -------------EDI---PELVDV----------WIQYSENHTYIQWKPLSHQQSHGIITGYKL 433

  Fly   650 QFNTSFTPAS-------WDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNKIGASPPSAHSDSCT 707
            ..||..:|.:       :..|.|...|             |...::.|.|..|.||||.     .
Zfish   434 TMNTIKSPVNIGANELCYSIASENEKN-------------NQIIKLSAKNSAGLSPPSV-----L 480

  Fly   708 TQPDVPFKN--------------------PDNVVGQGTE------PNNLVISWTPMPEIEHNAPN 746
            ..|..|.|.                    |.:..|...|      .....:.|..:||.:.:...
Zfish   481 IVPHDPGKGVSISLINSTNGGFEVFWKMYPKSTCGYVVEWFPTYNKTQCAVDWKKIPECDEDVCQ 545

  Fly   747 FHYYVSWKRDIPAAAWENNNIFDWRQNNIVIADQPTFVKYLIKVVAINDRGESNVAAEEVVGYSG 811
                 :|...:...|.|                     :|.|.|.|..:  .:.|..:...||:.
Zfish   546 -----TWIPPVEFKAGE---------------------RYTISVFACTN--GAPVLLQRSEGYAI 582

  Fly   812 EDRPLDAPTNFTMRQITSSTSGYMAWTPVSEESVRGHFKGYKIQTWTENEGEEGLREIHVKG--- 873
            |..|.....|...:|  :..:..::|..|:.:..:|...|||::. |.:|.::.::.|..|.
Zfish   583 EQEPQGTVQNLHGQQ--NGRNVELSWKEVALDQQKGIILGYKVKI-THSESKKVIKTIETKACEV 644

  Fly   874 ------DTHNALVTQFKPDSKNYARILAYNGRFNGPPSAVIDFDTPEGVPSPVQGLDAYPLGSSA 932
                  .::...|..|....::...||..|      ....||           |.|.|..:|.||
Zfish   645 ILPLDPGSYIFTVRAFTSVGESEDAILTMN------VETTID-----------QMLAATLVGCSA 692

  Fly   933 FML-------------HWKKP-LYPN-------GKLTGYKIYYEEVKESYVG-ERREY------- 968
            ..|             .|.|. |||:       ||.|...||..::.|.||. |.:|.
Zfish   693 ATLVFIIITVLCYRKREWLKDLLYPDIPEPKLAGKWTTQGIYCTQMTEGYVKCEIQEVHGSDHPT 757

  Fly   969 --DPHITDPRVTRMKMAGLKPNSKYRISITATTKMGEGSEHYIEKTTLKDAVNVAPATPSFSWEQ 1031
              :||..|...::..:...:| ..|..:.....|:....|:.....|....|:|
Zfish   758 SENPHGLDHHCSKKPLFPAQP-LYYNTTFPCAKKLTSIIENPSYNLTTPGPVDV----------- 810

  Fly  1032 LPSDNGLAKFRINWLPSTE-GHPGTH 1056
            :.:...|.:.:.::||::: ..|..|
Zfish   811 VQTSKPLLEMQDSYLPASKFAQPVCH 836

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.