| Sequence 1: | NP_001245581.1 | Gene: | Nrg / 31792 | FlyBaseID: | FBgn0264975 | Length: | 1309 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001361188.1 | Gene: | IL12RB2 / 3595 | HGNCID: | 5972 | Length: | 862 | Species: | Homo sapiens |
| Alignment Length: | 722 | Identity: | 141/722 - (19%) |
|---|---|---|---|
| Similarity: | 262/722 - (36%) | Gaps: | 205/722 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 409 GCNATNSLGYVYKDVYLNVQAEPPT-----ISEAPAAVSTVDGRNVTIKCRVNGSPKP------- 461
Fly 462 -------LVKWLRASNWLTGGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVKE 519
Fly 520 HTRITQEPQNYE-VAAGQSATFRC-----NEAH---DDTLEI----EIDWWKDGQSI-------- 563
Fly 564 ----------DFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARANLIVQDVPNAP 618
Fly 619 ---KLTGITCQADKAEIHWEQQGDNRSPILHYTIQFNTSFTPASWDAAYEKVPNTDSS----FVV 676
Fly 677 QMSPWANYTFRVIAFNKIGASPPSAHSDSCTTQPDVPFKNPDNVVGQGTEPNNLVISWTPMPEIE 741
Fly 742 HNAPN-----------------FHYYVSWKRDIPAAAWENNNIFDWRQNNIVIADQPTFVKYLIK 789
Fly 790 VVAINDRGESNVAAEEVVGYSGEDRPLDAPTNFTMRQITSSTSG----YMAWTPVSEESVRGHFK 850
Fly 851 GYKIQTWTENEGEEGLREIHVKGDTH-------------NALVTQFKPDSKNY----ARILAYNG 898
Fly 899 RFNGPPSAVIDFDTPEGVPSPVQG--LDAYPLGSSAFMLHWKK-PLYPN-GKLTGYKIYYEEVKE 959
Fly 960 SYVGERREYDPHITD-P-RVTRMK--MAGLKPNSKYRISITATTKMGEGSEHYIEKTTLKDAVN- 1019
Fly 1020 ---VAPA 1023 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nrg | NP_001245581.1 | Ig | 55..128 | CDD:299845 | |
| IG_like | 57..127 | CDD:214653 | |||
| Ig | 135..214 | CDD:299845 | |||
| IG_like | 141..216 | CDD:214653 | |||
| ig | 251..332 | CDD:278476 | |||
| I-set | 339..427 | CDD:254352 | 5/17 (29%) | ||
| Ig | 354..427 | CDD:299845 | 5/17 (29%) | ||
| I-set | 432..517 | CDD:254352 | 25/103 (24%) | ||
| Ig | 446..517 | CDD:299845 | 23/84 (27%) | ||
| I-set | 522..611 | CDD:254352 | 20/119 (17%) | ||
| ig | 525..609 | CDD:278476 | 20/114 (18%) | ||
| FN3 | 613..707 | CDD:238020 | 14/100 (14%) | ||
| FN3 | 716..807 | CDD:238020 | 18/107 (17%) | ||
| fn3 | 817..905 | CDD:278470 | 23/108 (21%) | ||
| FN3 | 917..1004 | CDD:238020 | 23/94 (24%) | ||
| FN3 | 1041..1111 | CDD:238020 | |||
| Bravo_FIGEY | 1155..>1221 | CDD:290593 | |||
| IL12RB2 | NP_001361188.1 | Lep_receptor_Ig | 28..110 | CDD:368845 | 21/92 (23%) |
| FN3 | 224..316 | CDD:238020 | 15/109 (14%) | ||
| WSXWS motif | 305..309 | 1/3 (33%) | |||
| FN3 | 423..511 | CDD:238020 | 23/108 (21%) | ||
| FN3 | 521..615 | CDD:238020 | 25/100 (25%) | ||
| Box 1 motif | 662..670 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 725..755 | ||||
| Required for STAT4 binding | 796..801 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 0 | 0.000 | |||||