| Sequence 1: | NP_001245581.1 | Gene: | Nrg / 31792 | FlyBaseID: | FBgn0264975 | Length: | 1309 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000085.1 | Gene: | COL7A1 / 1294 | HGNCID: | 2214 | Length: | 2944 | Species: | Homo sapiens |
| Alignment Length: | 1430 | Identity: | 284/1430 - (19%) |
|---|---|---|---|
| Similarity: | 467/1430 - (32%) | Gaps: | 487/1430 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 11 LLVALLCAG-SAESKGNRPPRITKQPAPGELLFKVAQQNKE---------SDNPFIIECEADGQP 65
Fly 66 EPEYSWIKNGKKFDWQAYDNRMLRQPG----RGTLVITIPKDEDRGHYQCFASNEFG--TATSNS 124
Fly 125 VYVRKAELNAFKDEAAKTLEA---VEGEPFMLKCAAPDGFPSPTV---NWMIQESIDGSIKSINN 183
Fly 184 SRMTL--------DPEGNLWFSNVTR--EDASSDFYYACSATSVFRSEYKIGNKVLLDVKQMGVS 238
Fly 239 ASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQTVWSKDGQRIQWSDRITQGHYGKSLV 303
Fly 304 IRQTNFDDAGTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEP 368
Fly 369 KISWIHNGKPIE-------------QSTPNPRRTVTDNTIRIINLVKGDTG--NYGCNATNSLGY 418
Fly 419 VYKDVYLNVQAEPPTISEA---PAAVSTVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGR--YN 478
Fly 479 VQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVKEHTRITQEP-QNYEVAA-------- 534
Fly 535 --GQSATFRCNEAHDDTL--------EIEIDW------------WKDGQSIDFEAQPRFVKTNDN 577
Fly 578 SLTIAKTMELDSG-EYTCVARTRLD--EATARANLIVQDVPNAPKL--TGIT-CQA-----DKAE 631
Fly 632 IHW--------------EQQGDNRSPILHYTIQFNTSFTPASWDAAYEKVPNTDSSF-VVQMSPW 681
Fly 682 ANYTFRVIAFNKIGASPPSAHSDSCTTQPDVPFKNPD--NVVGQGTEPNNLVISWTPMPEIEHNA 744
Fly 745 PNFHYYVSW--------KRDIPAAAWENNNIFDWRQNNIVIADQPTFVKYLIKVVAINDRGESNV 801
Fly 802 AAEEVVGYSGEDRPLDAPTNFTMRQITSSTSGYMAWTPVSEESVRGHFKGYKIQTWTENEGEEGL 866
Fly 867 REIHVKGDTHNALVTQFKPDSKNYARILAYNGRFNGPPSAVIDFDTPE--GVPSPVQGLDAYP-- 927
Fly 928 --------LGSSAFMLHWKKPLYPNGKLTGYKIYYEEVKESYVGERREYDPHITDPRVTRMKMAG 984
Fly 985 LKPNSKYRISITATTKMGEGSEHYIEKTTLKDAVNVAPATPS------------FSWEQLPSDNG 1037
Fly 1038 LAKFRINWLPSTEGHPGTHFFTMHRIKGETQWIRENEEKNSDYQEVGGLDPETAYEFRVVSVDGH 1102
Fly 1103 FNTESATQEIDTNTVEGP------IMVANETVANAGWFIGMMLALAFIIILFIIICIIRRNRGGK 1161
Fly 1162 YDVHDRELANGRRDYPEEGGFHEYSQPLDNKSAGRQSVSSANKPGVESDTDSMAEYGDGDTAVAT 1226
Fly 1227 AAARAAAAAR--SKLTSLPTSTQQQQQQQQQQQQQQEQ------PQSTSASTVPLISLASPSPSP 1283
Fly 1284 1283 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nrg | NP_001245581.1 | Ig | 55..128 | CDD:299845 | 14/78 (18%) |
| IG_like | 57..127 | CDD:214653 | 13/75 (17%) | ||
| Ig | 135..214 | CDD:299845 | 19/94 (20%) | ||
| IG_like | 141..216 | CDD:214653 | 18/90 (20%) | ||
| ig | 251..332 | CDD:278476 | 7/80 (9%) | ||
| I-set | 339..427 | CDD:254352 | 17/102 (17%) | ||
| Ig | 354..427 | CDD:299845 | 13/87 (15%) | ||
| I-set | 432..517 | CDD:254352 | 22/89 (25%) | ||
| Ig | 446..517 | CDD:299845 | 18/72 (25%) | ||
| I-set | 522..611 | CDD:254352 | 24/122 (20%) | ||
| ig | 525..609 | CDD:278476 | 24/117 (21%) | ||
| FN3 | 613..707 | CDD:238020 | 22/116 (19%) | ||
| FN3 | 716..807 | CDD:238020 | 19/100 (19%) | ||
| fn3 | 817..905 | CDD:278470 | 20/87 (23%) | ||
| FN3 | 917..1004 | CDD:238020 | 20/96 (21%) | ||
| FN3 | 1041..1111 | CDD:238020 | 17/69 (25%) | ||
| Bravo_FIGEY | 1155..>1221 | CDD:290593 | 16/65 (25%) | ||
| COL7A1 | NP_000085.1 | Nonhelical region (NC1) | 17..1253 | 275/1418 (19%) | |
| vWA_collagen_alphaI-XII-like | 37..201 | CDD:238759 | 35/185 (19%) | ||
| fn3 | 233..317 | CDD:278470 | 16/100 (16%) | ||
| fn3 | 333..407 | CDD:278470 | 22/99 (22%) | ||
| fn3 | 426..487 | CDD:278470 | 11/64 (17%) | ||
| fn3 | 509..587 | CDD:278470 | 17/101 (17%) | ||
| FN3 | 598..680 | CDD:238020 | 20/103 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 632..651 | 2/27 (7%) | |||
| FN3 | 687..771 | CDD:238020 | 22/93 (24%) | ||
| fn3 | 779..855 | CDD:278470 | 22/98 (22%) | ||
| FN3 | 867..952 | CDD:238020 | 24/106 (23%) | ||
| FN3 | 955..1044 | CDD:238020 | 21/115 (18%) | ||
| VWA | 1054..1227 | CDD:278519 | 14/52 (27%) | ||
| Cell attachment site. /evidence=ECO:0000255 | 1170..1172 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1239..1941 | ||||
| Triple-helical region | 1254..2784 | ||||
| Interrupted collagenous region | 1254..1477 | ||||
| Collagen | 1299..1353 | CDD:189968 | |||
| Cell attachment site. /evidence=ECO:0000255 | 1334..1336 | ||||
| Collagen | 1451..1504 | CDD:189968 | |||
| Collagen | 1764..1816 | CDD:189968 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1963..2782 | ||||
| Cell attachment site. /evidence=ECO:0000255 | 2008..2010 | ||||
| Collagen | 2022..2074 | CDD:189968 | |||
| Collagen | 2108..2166 | CDD:189968 | |||
| Collagen | 2242..2301 | CDD:189968 | |||
| Collagen | 2324..2369 | CDD:189968 | |||
| Collagen | 2466..2520 | CDD:189968 | |||
| Collagen | 2527..2598 | CDD:189968 | |||
| Cell attachment site. /evidence=ECO:0000255 | 2553..2555 | ||||
| Collagen | 2614..2673 | CDD:189968 | |||
| Collagen | 2650..2707 | CDD:189968 | |||
| Nonhelical region (NC2) | 2785..2944 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2837..2872 | ||||
| KU | 2874..2930 | CDD:238057 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 0 | 0.000 | |||||