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Protein Alignment Nrg and ncam2

DIOPT Version :10

Sequence 1:	NP_001245581.1	Gene:	Nrg / 31792	FlyBaseID:	FBgn0264975	Length:	1309	Species:	Drosophila melanogaster
Sequence 2:	XP_012811963.1	Gene:	ncam2 / 100151722	XenbaseID:	XB-GENE-1217730	Length:	865	Species:	Xenopus tropicalis

Alignment Length:	993	Identity:	195/993 - (19%)
Similarity:	346/993 - (34%)	Gaps:	304/993 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 WSKDGQRIQWSDRITQGHYG--KSLVIRQTNFDDAGTYTCDVSNGVGNAQSFSIILNV------N 336
            ::..|::|....|:.....|  ..|.|.:.|.||||.|.|..::..|:||..:::|.:      .
Frog    83 FNPQGEKIISGQRVVVQREGIRSWLTIYKANVDDAGIYRCQATDSKGHAQEATVVLEIYQKLTFE 147

  Fly   337 SVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDNTIRIINLV 401
            .||    .|:.....|:.||:  |..:..|.|.:.|::|.:.:..........:.:|.::|.|:.
Frog   148 DVP----SPQEFKRGENAEVL--CLVSSSPAPMVRWLNNREDVTDIDDRRFAMLPNNNLQIKNIS 206

  Fly   402 KGDTGNYGCNATNSL-GYV-YKDVYLNVQAEPPTISEAPAAVSTVDG-RNVTIKCRVNGSPKPLV 463
            |.|.|.|.|.....: |.: ::|:.:.|...|..:::..:..:|.|. .::|:.||..|||||.:
Frog   207 KRDEGIYRCEGRVEVRGEIDFRDISVIVNVPPEILAQQRSFNATADRLEDITLFCRATGSPKPYI 271

  Fly   464 KWLRASNWL-TGGRYNV-QANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVKEHTRITQE 526
            .|.|....: ...:|:: :.|.:|.::::..:|:|.|.|.|.||.|..:....|.|.....|.|.
Frog   272 TWHRNGKLVEENEKYDLREDNTELTVKNIISTDSGLYVCRATNKAGFTEKQSFLQVFVQPHIVQL 336

  Fly   527 PQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSIDF----EAQPRFVKT----NDNSLTIAK 583
            .....:..|. .|..| ||..:.:. ||.|.:....:.|    ::|...:::    ..:||.|..
Frog   337 QNETTIEHGH-VTLTC-EAEGEPIP-EITWKRSSDGMIFYDGDKSQDGRIESTGHHGKSSLHIKS 398

  Fly   584 TMELDSGEYTCVARTRLDEATARANLIVQDVPNAPKLTGITCQADKAEIHWEQQGDNRSPILHYT 648
            .|..|:|.|.|.|.:|:.   .....:..::..|||.                       |.:.|
Frog   399 VMLSDAGRYDCEAASRIG---GHQKSMYLNIEYAPKF-----------------------ISNQT 437

  Fly   649 IQFNTSFTPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNKIGASPPSAHSDSCTTQPDVP 713
            |.:       ||:
Frog   438 IYY-------SWE---------------------------------------------------- 443

  Fly   714 FKNPDNVVGQGTEPNNLVISWTPMPEIEHNAPNFHYYVSWKRD---IPAAAWENNNIFDWRQNNI 775
             .||.|:                ..::..|.|:..|   |.||   :||.  ...||..:|....
Frog   444 -NNPINI----------------SCDVTSNPPSSIY---WSRDKLLLPAR--NITNIKTYRDGKR 486

  Fly   776 VIADQPTFVKYLIKVVAINDRGESNVAAEEVVGYSGEDRPLDAPTNFTMRQITSSTSGYMAWTPV 840
            ::.:        |..::.||.|..|..|...:|...::..|      |:..:.||
Frog   487 ILLE--------ITPLSDNDFGRYNCTAINSIGSRIQEYIL------TLADVPSS---------- 527

  Fly   841 SEESVRGHFKGYKIQTWTENEGEEGLREIHVKGDTHNALVTQFKPDSKNYARILAYNGRFNGPPS 905
                                  ..|||.|.:               |:.||::.     ||.|
Frog   528 ----------------------PYGLRVIEL---------------SQTYAKVF-----FNKP-- 548

  Fly   906 AVIDFDTPEGVPSPVQGLDAYPLGSSAFMLHWKKPLYPNGKLTGYKIYYEEVKESYVGERREYDP 970
                 |:..|||                 :|            .|::.::||........|.:..
Frog   549 -----DSHGGVP-----------------IH------------HYQMDFKEVSSEIWKVVRSHGT 579

  Fly   971 HITDPRVTRMKMAGLKPNSKYRISITATTKMGEGSEHYIEKTTLKDAVNV-APATPSFSWEQLPS 1034
            .      |.:.:..|..|:.|.:.:.|....|:|.   ..||.:...:.| .|:.||...:
Frog   580 Q------TIIVLGNLDANTTYEVKVAAVNGKGKGE---YSKTEIFQTLPVREPSPPSIHGQ---- 631

  Fly  1035 DNGLAKFRINWLPSTE-GHPGTHFFTMHRIKG-ETQWIRENEEKNSDYQEVGGLDPETAYEFRVV 1097
            ..|...|:::.....: |.|..::...:|.|. |.||:.:....|.||..:..|.....||..::
Frog   632 PGGGKSFKLSITKQDDGGAPILNYVVKYRSKDKEDQWLEKKFLGNKDYIILDHLQWNVGYEVHII 696

  Fly  1098 SVD--GHFNTESATQEIDTNTVEGPIMVANETVANAGWFIGMMLALAFIIILFIII--------- 1151
            :.:  ||    |.....:......|.::|:...:..|  :|.::.||...:|.:::
Frog   697 ATNRLGH----SEPTVFEFLMPPKPNIIADTLFSGLG--VGAVIGLAVAALLLVLVVTDVSCFFI 755

  Fly  1152 -------CIIRRNRG------GKYDVHDRELANGRRDYPEEGGFHEYSQPL-----DNKSAGRQS 1198
                   ||.||..|      ||    .:||..|:..|.::|.    .:|:     :::......
Frog   756 RQCGLLMCITRRICGKKSGSSGK----SKELEEGKAAYLKDGS----KEPIVEMRTEDERVTNHD 812

  Fly  1199 VSSANKPGVESDTDSMAE 1216
            .|..|:|   ::|..:.|
Frog   813 GSPVNEP---NETTPLTE 827

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.