Protein Alignment Spn75F and SERPINB7

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_003775.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 70/377 - (18%)
• Similarity: 153/377 - (40%)
• Gaps: 55/377 - (14%)

  Fly    22 FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQL-------------TG 73
            |..||.:::...:...|..:|.:::..||.|:.|...:.:..|::..|.:             :|
Human    11 FCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNSSNSQSG 75

  Fly    74 LNQEEIISLFKEAREKVAQEQFTMGNRIYLSPDYNASPNITQLSENL-GVEVKNMTFSGDQSAAS 137
            | |.::..:|.:..........::.|.::....|....:..:.:|.| ..:|:.:.|:   :...
Human    76 L-QSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFT---NHLE 136

  Fly   138 EIKKWLNKWI-----GKAGGNLFGKNDISQTTQIVAVQGMSYSCVWKNRETALTNRTFTLLRQNK 197
            :.::.:|||:     ||. .|:.|:..||.:..:|.|..:.:...|::..|  .:.|.....::.
Human   137 DTRRNINKWVENETHGKI-KNVIGEGGISSSAVMVLVNAVYFKGKWQSAFT--KSETINCHFKSP 198

  Fly   198 KPFVYTTQMMYTEAPMDFFN----NDQVRGVMVPFKNSDMGMLVLLPRPRYSTQQILYSLDTILK 258
            |.......||:.|..   ||    .|....::....|..:.|.||||....|..:...:...:::
Human   199 KCSGKAVAMMHQERK---FNLSVIEDPSMKILELRYNGGINMYVLLPENDLSEIENKLTFQNLME 260

  Fly   259 -IKLRR--SKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNA-------------ANFKQYN 307
             ...||  ||...:|.|:||:.::.::...|:|||::::|..:.|             :.....:
Human   261 WTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKS 325

  Fly   308 SFDADQNRVLMTIDVGDDFDDR------VVYVNRGFVFVVKDKSTIYMIGRM 353
            ..:..:.....|...|.:..::      :...:..|:||::....|...|::
Human   326 YIEVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVIRKDDIILFSGKV 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	69/374 (18%)
SERPINB7	NP_003775.1	serpinB7_megsin	1..380	CDD:381032	70/377 (19%)