Protein Alignment Spn75F and Serpina3a

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001161177.1
• Gene: Serpina3a / 74069
• MGIID: 1921319
• Length: 422
• Species: Mus musculus
• Alignment Length: 383
• Identity: 86/383 - (22%)
• Similarity: 161/383 - (42%)
• Gaps: 71/383 - (18%)

  Fly    21 NFEINLTKQLSKGRLARNFVYSPIAIRQALGLLYL-SKDNVTDQQLES-ALQLTGLNQEEIISLF 83
            :|..:|.|:|:.....:|.|:||::|..||.|:.| :|||..::.||. ...||...:.:|...|
Mouse    55 DFAFSLYKKLALKNPHKNIVFSPLSISAALALMSLGAKDNTLEEILEGLKFNLTETPEADIHQNF 119

  Fly    84 KEAREKVAQE----QFTMGNRIYLSPDYNASPNITQLSENLGVEVKNMTFSGDQSAASEIKKWLN 144
            ....:.:.|.    |...||.:::......   :|:..|......|...|:.|.....|..|.:|
Mouse   120 GHLLQMLIQPENQVQINAGNALFIDKHLQI---LTEFKEKARALYKAEAFTADFQLPREATKLIN 181

  Fly   145 KWIGKAGGNLFGK-----NDISQTTQIVAVQGMSYSCVWK----NRETALTNRTFTLLRQNKKPF 200
            .::.|   ...||     :|:.:.|.:..|..:::...|.    ..:|.|.|  |||   ::|..
Mouse   182 DYVRK---QTQGKIKELVSDLHRNTSMALVNFLNFQGFWNVTFDPEDTFLGN--FTL---DRKRT 238

  Fly   201 VYTTQMMYTEAPMDFFNNDQVRGVMVPFKN-SDMGMLVLLPRPRYSTQQILYSLDTILKIKLRRS 264
            |....|...|...::|.:::::..::.... .:...|.:||    ...:|.:..|::....||:.
Mouse   239 VNVPMMKTEELTTNYFRDEEMQSTVMELNYIGNASFLFILP----DQGRIQHVEDSLQPQSLRKW 299

  Fly   265 KKT-------HLFLPKFKVSESVDLNMALKALGIQNLFTN-------TNAANFKQYNSFDADQNR 315
            :|:       .|.||||.:|:..:||..|..|||:.:|:.       |.|.|.:      ..|..
Mouse   300 RKSLRPRMLDELSLPKFSLSQDYNLNDILPELGIKEVFSTQADLSGITGAKNIR------VSQMI 358

  Fly   316 VLMTIDVGDDFDD------------------RVVYVNRGFVFVVKDK--STIYMIGRM 353
            ....:||.:...:                  ::|.|:|.|::::.|.  .:|.::|::
Mouse   359 HQAALDVTETHTEADVITIARYNFQSAKIKAKIVKVDREFLYLILDPMFKSISVMGKV 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	85/380 (22%)
Serpina3a	NP_001161177.1	serpinA3_A1AC	39..419	CDD:381019	86/383 (22%)