Protein Alignment Spn75F and SERPINF2

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_005256758.2
• Gene: SERPINF2 / 5345
• HGNCID: 9075
• Length: 507
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 84/362 - (23%)
• Similarity: 151/362 - (41%)
• Gaps: 63/362 - (17%)

  Fly    22 FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQL-TGLNQEEIISLFKE 85
            |..:|...:::.....|.:.||:::..||..|.|...|.|.|:|:..|.. :|.....::|
Human   105 FTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLS---- 165

  Fly    86 AREKVAQE----QFTMGNRIYLSPDYNASPNITQLSENL-GVEVKNMTFSGDQSAASEIKKWLNK 145
               ::.|:    .|.:..|:||...:....:..:.||.| |.:..::|...:...|:     :|:
Human   166 ---RLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLAN-----INQ 222

  Fly   146 WI-----GKAGGNLFGKNDISQTTQIVAVQGMSYSCVWKNR-ETALTNR-TFTLLRQNKKPFVYT 203
            |:     ||....|.|   :.:.|.::.:..:.:...|:|: :.:||.| :|.|..|    |...
Human   223 WVKEATEGKIQEFLSG---LPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQ----FTVP 280

  Fly   204 TQMMYTEA-PMDFF--NNDQVRGVMVPFKNSDMGMLVLLPRP-RYSTQQILYSL--DTILKIKLR 262
            .:||.... |:.:|  ...:::....|||| :|..:||:|.. .::..|:|.:|  || |...|.
Human   281 VEMMQARTYPLRWFLLEQPEIQVAHFPFKN-NMSFVVLVPTHFEWNVSQVLANLSWDT-LHPPLV 343

  Fly   263 RSKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNAANFKQYNSF--DADQNRVLMTIDVG-- 323
            ..:.|.:.|||..:...:||...|..||:|.||...:.....:.:..  .......|...:||
Human   344 WERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVE 408

  Fly   324 --------------DDFDDRVVYVNRGFVFVVKDKST 346
                          ..|.     |||.|:|.:.:.:|
Human   409 AAAATSIAMSRMSLSSFS-----VNRPFLFFIFEDTT 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	84/362 (23%)
SERPINF2	XP_005256758.2	serpinF2_A2AP	91..454	CDD:381009	84/362 (23%)