Protein Alignment Spn75F and SERPINI1

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_005016.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 75/383 - (19%)
• Similarity: 163/383 - (42%)
• Gaps: 66/383 - (17%)

  Fly    21 NFEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQLTGLNQEEIISLFKE 85
            :..:|:..:|.......|.::||::|..|:|::.|.....|.:::..::....|...|..|..||
Human    28 DLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKE 92

  Fly    86 AREKVA--QEQFTM--GNRIYLSPDYNASPNITQLSEN-LGVEVKNMTFSGDQSAASEIKKWLNK 145
            ....|.  :.|:.|  .|.:::...::.:....|:.:. ....|.::.||.:.:.|:.|.||:..
Human    93 FSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVEN 157

  Fly   146 WIGKAGGNLFGKNDISQTTQIVAVQGMSYSCVWKNRETALTNRTFTLLRQNKKPFVYTTQMMYTE 210
            .......:|....|....|.:..:..:.:...||::......|||:..:.::..  ....|||.:
Human   158 NTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESE--VQIPMMYQQ 220

  Fly   211 APMDFF------NNDQVRGVM----VPFKNSDMGMLVLLPRPRYSTQQI-LYSLDTILKIKL--- 261
            .  :|:      .:::..|:.    :|::..::.|:::|.|     |:: |.:|:.::|.:|
Human   221 G--EFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSR-----QEVPLATLEPLVKAQLVEE 278

  Fly   262 ----RRSKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNAANFKQYNSFDADQNRVLMT--- 319
                .:.:|..::||:|.|.:.:||...||||||..:|       .|..|......|:.:..
Human   279 WANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-------IKDANLTGLSDNKEIFLSKA 336

  Fly   320 -----IDVGDDFDDRV-----------------VYVNRGFVFVVKDK--STIYMIGRM 353
                 ::|.::..:..                 |.|:..|.|:::::  .||..:||:
Human   337 IHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	73/380 (19%)
SERPINI1	NP_005016.1	serpinI1_NSP	23..394	CDD:381005	74/381 (19%)