Protein Alignment Spn75F and SERPINB8

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 76/312 - (24%)
• Similarity: 136/312 - (43%)
• Gaps: 34/312 - (10%)

  Fly    22 FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQL--TGLNQEEIISLFK 84
            |.|:|.|.|.:...:||..:||::|..||.::::.....|..|:..||.|  .|.......||..
Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIHRGFQSLLS 75

  Fly    85 EAREKVAQEQFTMGNRIYLSPDYNASPNITQLSENL-GVEVKNMTFSGDQSAASEIKKWLNKWIG 148
            |......|......||::.....:..|:..:..:.. ..|::.::|:.|   ..|.:|.:|.|:.
Human    76 EVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAED---TEECRKHINDWVA 137

  Fly   149 -KAGGNL---FGKNDISQTTQIVAVQGMSYSCVWKNRETALTNRTFT---LLRQNKKPFVYTTQM 206
             |..|.:   .....:...|::|.|..:.:...|..:    .:|.:|   |.:.|::.  .|.||
Human   138 EKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQ----FDRKYTRGMLFKTNEEK--KTVQM 196

  Fly   207 MYTEAPMDFFNNDQV--RGVMVPFKNSDMGMLVLLPRPRYSTQQILYSLDTILKI-------KLR 262
            |:.||.......|:|  :.:.:|:...::.|::|||........:..:| |..|.       ||.
Human   197 MFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL-TYEKFKAWTNSEKLT 260

  Fly   263 RSKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNAANFKQYNSFDADQN 314
            :| |..:|||:.|:.||.||...|:.||:.:.|....|    .::....::|
Human   261 KS-KVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKA----DFSGMSTEKN 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	76/312 (24%)
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	76/312 (24%)