Protein Alignment Spn75F and SERPINA10

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 83/394 - (21%)
• Similarity: 162/394 - (41%)
• Gaps: 97/394 - (24%)

  Fly    21 NFEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQLTGLNQEE---IISL 82
            ||..:|.:::|. |...|.|:||..:..|:..|.|.....|:.|::..|.|..|...:   :.||
Human   121 NFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSL 184

  Fly    83 FKEAREKVAQE---QFTMGNRIYLSPDYNASPNITQLSEN-LGVEVKNMTFSGDQSAASEIKKWL 143
            ||..||.:::.   ..|.|:..::..|::.......||:. ...|...|.|..    ||:.|:.:
Human   185 FKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN----ASQAKRLM 245

  Fly   144 NKWIGKAGGNLFGK--NDISQTTQIVAVQGMSYSCVWKNRETALTNRTFTLLRQNKKPFVYTTQM 206
            |.:|.|.......|  ::|:..|:::.|..:.:...|      ||            ||    ..
Human   246 NHYINKETRGKIPKLFDEINPETKLILVDYILFKGKW------LT------------PF----DP 288

  Fly   207 MYTEAPMDFFNNDQVRGVMVP-----------FKNSDMGMLVLLPRPRYSTQQIL---------- 250
            ::||  :|.|:.|:.:.:.||           |..:....::.||....:|..::
Human   289 VFTE--VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA 351

  Fly   251 ---YSLDTILKIKLR--RSKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNAANFKQYNSFD 310
               |....:::..||  :::...:|.||||:.:..:::..|:.:||:.:|     :.|...:...
Human   352 LEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF-----SPFADLSELS 411

  Fly   311 A-----DQNRVLMTIDVGDDFDDR-------------------VVYVNRGFVFVVKDKST--IYM 349
            |     ..:|||....:  :.|:|                   |:.|:|.|.|::.::::  :..
Human   412 ATGRNLQVSRVLQRTVI--EVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLF 474

  Fly   350 IGRM 353
            :||:
Human   475 LGRV 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	81/391 (21%)
SERPINA10	XP_016876842.1	serpinA10_PZI	107..482	CDD:381011	83/394 (21%)