DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn75F and Spn43Aa

DIOPT Version :9

Sequence 1:	NP_001036614.1	Gene:	Spn75F / 317912	FlyBaseID:	FBgn0052203	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	78/379 - (20%)
Similarity:	149/379 - (39%)	Gaps:	68/379 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQLTGLNQEEIISLFKEA 86
            |...|.:.|:..|...|.:.||::|:.||||.|...:..|..:|:..|..:.          ||:
  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASA----------KES 84

  Fly    87 REKVAQEQFTM-------------GNRIYLSPDYNASPNITQLSEN-LGVEVKNMTFSGDQSAAS 137
            ::.:|:....:             .|::|...:...|.:..::::. ...||:.:.||.:..|..
  Fly    85 KDGLAESYHNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVE 149

  Fly   138 EIKKWLNKWIGKAGGNLFGK--NDISQTTQIVAVQGMSYSCVWKN--RETALTNRTFTL--LRQN 196
            :|    |:|:.:...|...:  ..:...|.:..|..:.:...|..  .:....:|.|.|  .|..
  Fly   150 QI----NRWVKQQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSI 210

  Fly   197 KKPFVYTTQMMYTEAPMDFFNNDQVRGVMVPFKNSDMGMLVLLPRPRYSTQ---QILYSLDTILK 258
            :.|.::.....|.   .|:...| .:.:.:.|:|.::.|..:||..|...|   |.|..:|..|.
  Fly   211 QVPTMFADNWYYY---ADYPELD-AKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLL 271

  Fly   259 IKLRRSKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNAANFK---------------QYNS 308
            ....:.:...::|||||.....||...|..:||..:|  ::||:|.               |:.:
  Fly   272 EDRWQWQSVSVYLPKFKFEFDTDLRPTLHKMGISAMF--SDAADFSNIFQDSPIGTRITKVQHKT 334

  Fly   309 FDADQNRV---------LMTIDVGDDFDDRVVYVNRGFVFVVKDKSTIYMIGRM 353
            | .|.|.:         ...:.:....|.:....:..|.|:::||..:|..|.:
  Fly   335 F-IDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDKHAVYFTGHI 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	SERPIN	21..353	CDD:294093	78/377 (21%)
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	78/377 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940