Protein Alignment Spn75F and SERPINA9

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_783866.3
• Gene: SERPINA9 / 327657
• HGNCID: 15995
• Length: 417
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 83/392 - (21%)
• Similarity: 156/392 - (39%)
• Gaps: 79/392 - (20%)

  Fly    18 YAYN--FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQLTGLN----- 75
            |:.|  |...|.::|.....::|..:||:::..:|.:|.|...:||..|:   ||..|.|
Human    45 YSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQI---LQGLGFNLTHTP 106

  Fly    76 --------QEEIISLFKEAREKVAQEQFTMGNRIYLSPDY----NASPNITQLSENLGVEVKNMT 128
                    |..:.||...:::...:    ||:.:::..:.    |...|:.:|.|   .||.:..
Human   107 ESAIHQGFQHLVHSLTVPSKDLTLK----MGSALFVKKELQLQANFLGNVKRLYE---AEVFSTD 164

  Fly   129 FSGDQSAASEIKKWLNKWIGKAGGNLFGKNDISQ----TTQIVAVQGMSYSCVW-KNRETALTNR 188
            ||....|.:.|...:.|   |..|.:.   ||.|    .|.:|.|..:.:...| |......|.:
Human   165 FSNPSIAQARINSHVKK---KTQGKVV---DIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRK 223

  Fly   189 TFTLLRQNKKPFVYTTQ------MMYTEAPMDFFNNDQVR--GVMVPFKNSDMGMLVLLPRPRYS 245
            .|        ||:...|      ||:.:....|..:.::.  .:.:.:|...:...||..:.:..
Human   224 NF--------PFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMR 280

  Fly   246 TQQILYSLDTILKIKLRRSKK-THLFLPKFKVSESVDLNMALKALGIQNLF-TNTNAANFKQYNS 308
            ..:...|..|:.|......|: ..:|:|:|.:|.|.:|...|..:||||:| .|.:.:...:.:|
Human   281 QLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDS 345

  Fly   309 FDADQNRVLMTIDVGDDFDDR-------------------VVYVNRGFVFVVKDKST--IYMIGR 352
            ....:......:||.::..:.                   .|..||.|:.::.:|:|  |..:|:
Human   346 LQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGK 410

  Fly   353 MD 354
            ::
Human   411 VE 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	81/386 (21%)
SERPINA9	NP_783866.3	serpinA9_centerin	30..417	CDD:381024	83/392 (21%)