Protein Alignment Spn75F and Serpina1c

DIOPT Version :10

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_033271.1
• Gene: Serpina1c / 20702
• MGIID: 891969
• Length: 413
• Species: Mus musculus
• Alignment Length: 326
• Identity: 76/326 - (23%)
• Similarity: 126/326 - (38%)
• Gaps: 79/326 - (24%)

  Fly    16 HSYAYN---FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQ--LTGLN 75
            |..|.|   |.|:|.::|.......|..:||::|..|..:|.|.....|..|:...||  ||..:
Mouse    42 HEIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTS 106

  Fly    76 QEEIISLFKEAREKV----AQEQFTMGNRIYLSPDYNASPNITQLSENLGVEVKN----MTFSGD 132
            :.:|...|:...:.:    ::.|.:.||.::::.|       .:|.|....|.||    ..||.:
Mouse   107 EADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNND-------LKLVEKFLEEAKNHYQAEVFSVN 164

  Fly   133 QSAASEIKKWLNKWIGKAGGNLFGKNDISQTTQIVAVQGMSYSCVWK-NRETALTNRTFTLLRQN 196
            .:.:.|.||.:|.::.|                  ..||.....|.| :::|......:.|.:..
Mouse   165 FAESEEAKKVINDFVEK------------------GTQGKIAEAVKKLDQDTVFALANYILFKGK 211

  Fly   197 -KKPF-VYTTQMMYTEAPMDFFNNDQVRGVMVPFKNSDMGML----------------------- 236
             |||| ...|:    ||.   |:.|:...|.||..... |||
Mouse   212 WKKPFDPENTE----EAE---FHVDESTTVKVPMMTLS-GMLDVHHCSTLSSWVLLMDYAGNATA 268

  Fly   237 -VLLP---RPRYSTQQILYSLDTILKIKLRRSKK-THLFLPKFKVSESVDLNMALKALGIQNLFT 296
             .|||   :.::..|.:  |.:.|.|..|:|.:: ..:..|:..:|...:|...:..|||..:|.
Mouse   269 VFLLPDDGKMQHLEQTL--SKELISKFLLKRPRRLAQIHFPRLSISGEYNLKTLMSPLGITRIFN 331

  Fly   297 N 297
            |
Mouse   332 N 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	74/322 (23%)
Serpina1c	NP_033271.1	serpinA1_A1AT	44..412	CDD:381012	75/324 (23%)