Protein Alignment Spn75F and SERPINA3

DIOPT Version :9

• Sequence 1: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001076.2
• Gene: SERPINA3 / 12
• HGNCID: 16
• Length: 423
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 85/385 - (22%)
• Similarity: 157/385 - (40%)
• Gaps: 74/385 - (19%)

  Fly    21 NFEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQ--LTGLNQEEIISLF 83
            :|..:|.|||......:|.::||::|..||..|.|...|.|..::...|:  ||..::.||...|
Human    55 DFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSF 119

  Fly    84 KEAREKVAQE----QFTMGNRIYLSPDYNASPNITQLSENL-GVEVKNMTFSGDQSAASEIKKWL 143
            :.....:.|.    |.:|||.:::....:.....|:.::.| |.|    .|:.|...::..||.:
Human   120 QHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSE----AFATDFQDSAAAKKLI 180

  Fly   144 NKWIGKAGGNLFGK-----NDISQTTQIVAVQGMSYSCVWK---NRETALTNRTFTLLRQNKKPF 200
            |.:: |.|..  ||     .|:...|.:|.|..:.:...|:   :.:....:|.:.    :||.:
Human   181 NDYV-KNGTR--GKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYL----SKKKW 238

  Fly   201 VYTTQMMYTEAPMDFFNNDQVRGVMVPFK-NSDMGMLVLLPRPRYSTQQILYSLDT-ILKIKLRR 263
            |....|......:.:|.::::...:|..| ..:...|.:||     .|..:..::. :|...|:|
Human   239 VMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILP-----DQDKMEEVEAMLLPETLKR 298

  Fly   264 SKKT-------HLFLPKFKVSESVDLNMALKALGIQNLFTN-------TNAANFKQYNSFDADQN 314
            .:.:       .|:||||.:|...:||..|..|||:..||:       |.|.|..      ..|.
Human   299 WRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLA------VSQV 357

  Fly   315 RVLMTIDVGDDFDD-------------------RVVYVNRGFVFVV--KDKSTIYMIGRM 353
            .....:||.::..:                   .:|..||.|:.::  .|...|:.:.::
Human   358 VHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKV 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn75F	NP_001036614.1	SERPIN	21..353	CDD:294093	85/383 (22%)
SERPINA3	NP_001076.2	serpinA3_A1AC	40..421	CDD:381019	85/385 (22%)
		RCL	369..394		0/24 (0%)
		O-glycosylated at one site	381..389		0/7 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910