DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32201 and CG31016

DIOPT Version :9

Sequence 1:	NP_730346.2	Gene:	CG32201 / 317911	FlyBaseID:	FBgn0052201	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001263119.1	Gene:	CG31016 / 326113	FlyBaseID:	FBgn0051016	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	157/531 - (29%)
Similarity:	275/531 - (51%)	Gaps:	34/531 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SLLPVLLGFAVLNSFVGCVEDIEEKERYSSSTVGLLKLLKVEEKFTDNLLNQVDQLGEKFEALRM 70
            |::...:.|.::.|::  .|...:::.|..|....:.||:.:.:....|.:...:|.||...|:.
  Fly     3 SVVLFAVSFILVLSWI--AEGYRDRQNYVISVEEKMDLLEKDRELIIVLDSYATELNEKIIMLKR 65

  Fly    71 YLSSVGYELHRSLNEKVQYVSNPINAFSLLRRTHEDLPKWHEYFKEAIGEGNQSILVDLVKMVPN 135
            .:......|.::.|.:.:|:||||::.||:|:.|||..|..:..|:.:|:...:::..:.:.:|.
  Fly    66 IVKEFKQPLEKAKNREEEYLSNPIDSLSLMRQMHEDWEKVEKLLKKPVGQEKIALVEKMREDLPV 130

  Fly   136 DVDMLSAMHGIQRIEKIYDLKIDDLAQGVLQGVQYNVQLTYRDLIAMGNSMYQQSDYQTAAKWYR 200
            :.|::.|...:.||...|||:..|::.|.:.||||..:::..|...||...:....||.|:||..
  Fly   131 ENDLMEANQAMFRILHTYDLEPKDVSAGWIDGVQYGGKMSASDCFTMGTFSFMAGSYQIASKWLS 195

  Fly   201 IACKRELENPEQLFIQILGDPSEHLHRQYIKSLFKYGSTTSEPSKSIEEAFIMVQASQEELDNIM 265
            .|....::.|.: :.:::|.....:.....:||...|: .|..:..:...|:..:|......:.:
  Fly   196 AAKDLLVDQPRK-YHEVMGITKADVTLLLARSLIASGN-VSIATDMLMRDFMFGEAGSALTVHFL 258

  Fly   266 SDLNEPQNDVEVE-----KDLYQVKRSPSNCELGCRGLYRQKTNLVCRYKSTANTFLRLAPLKLE 325
            .  |:|:..:.:|     :...|:.||.|..::|    ..:.:.|.|||.:....||:|||.::|
  Fly   259 R--NKPKPSINLESWESDESFNQLCRSSSRRQMG----ESKPSRLHCRYNTITTPFLKLAPFRME 317

  Fly   326 EISLDPFMAMYHEVLYDSEIRELKGQS---MNMVNGYASQRNGTEIRDTVVRYD--WWSNTSL-- 383
            |:||||::..||.||.|:||.:||...   :.....:..::...|| |.....|  |..:.::
  Fly   318 ELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAKVFRVEKGSDEI-DPSRSADGAWLPHQNIDP 381

  Fly   384 ----VRERINQRIIDMTGFNFLKDEKLQIANYGLGTYFQPHFDYSSDGFETPNITTLGDRLASIL 444
                |..||.:||.||||.|.....|:|...||.|.:|.||:||.:.  :|.::.|:|||:|::|
  Fly   382 DDLEVLNRIGRRIEDMTGLNTRSGSKMQFLKYGFGGHFVPHYDYFNS--KTFSLETVGDRIATVL 444

  Fly   445 FYASEVPQGGATVFPEINVTVFPQKGSMLYWFNLHDDGKP---DIRSLHSVCPVLNGDRWTLTKW 506
            ||.:.|..|||||||::|:.|..||||.|:|.|:  |.|.   |.|:.|..||:::|.:..:|:|
  Fly   445 FYLNNVDHGGATVFPKLNLAVPTQKGSALFWHNI--DRKSYDYDTRTFHGACPLISGTKLVMTRW 507

  Fly   507 VPMFPQMFSFP 517
            :....|||..|
  Fly   508 IYELDQMFLIP 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32201	NP_730346.2	P4Ha_N	36..165	CDD:285528	34/128 (27%)
CG32201	NP_730346.2	P4Hc	341..507	CDD:214780	65/179 (36%)
CG31016	NP_001263119.1	P4Ha_N	31..160	CDD:285528	34/128 (27%)
CG31016	NP_001263119.1	P4Hc	333..508	CDD:214780	65/179 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461907
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910