Protein Alignment CG32201 and P4HA3

DIOPT Version :9

• Sequence 1: NP_730346.2
• Gene: CG32201 / 317911
• FlyBaseID: FBgn0052201
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001275677.1
• Gene: P4HA3 / 283208
• HGNCID: 30135
• Length: 604
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 126/488 - (25%)
• Similarity: 202/488 - (41%)
• Gaps: 110/488 - (22%)

  Fly    38 VGLL-KLLKVEE-------KFTDNLLNQVDQLGEKFEALRMYLSSVGYELHRSLNEKVQYVSNPI 94
            :||| :.|:.||       :|.|.:|:                      ||   .:....|:||:
Human    48 LGLLRRYLRGEEARLRDLTRFYDKVLS----------------------LH---EDSTTPVANPL 87

  Fly    95 NAFSLLRRTHEDLPKWHEYFKEAIGEGNQSILVDLVKMVPNDV----DMLSAMHGIQRIEKIYDL 155
            .||:|::|...|   |...........|...|.|..:.|..|:    |:..|...:.|::.:|.|
Human    88 LAFTLIKRLQSD---WRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYML 149

  Fly   156 KIDDLAQGVLQGVQYNV-----------QLTYRDLIAMGNSMYQQSDYQTAAKWYRIACKRELEN 209
            .:..||:||.|.|..:.           .||..|...:|...|...||..|..|        ||.
Human   150 NVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYHAIPW--------LEE 206

  Fly   210 PEQLFIQILG-----------DPSEHLHRQYIKSLFKYGSTTSEPSKSIEEAFIMVQASQEEL-D 262
            ...||....|           |..:||...|    |:.|:.:.  :.|:...|::.....:.: .
Human   207 AVSLFRGSYGEWKTEDEASLEDALDHLAFAY----FRAGNVSC--ALSLSREFLLYSPDNKRMAR 265

  Fly   263 NIMSD---LNEPQNDVEVE-------------KDLYQVKRSPSNCE-LGCRGLYRQKTNLVCRYK 310
            |::..   |.|..|.|..|             :|.|:     ..|: ||.:....|..:|.|.|:
Human   266 NVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDTYE-----GLCQTLGSQPTLYQIPSLYCSYE 325

  Fly   311 STANTFLRLAPLKLEEISLDPFMAMYHEVLYDSE---IRELKGQSMNMVNGYASQRNGTEIRDTV 372
            :.:|.:|.|.|::.|.|.|:|::|:||:.:.|||   |||| .:.....:..||.....::...:
Human   326 TNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIREL-AEPWLQRSVVASGEKQLQVEYRI 389

  Fly   373 VRYDWWSNT---SLVRERINQRIIDMTGFNFLKD--EKLQIANYGLGTYFQPHFDYSSDGFETPN 432
            .:..|..:|   .||  .:|.||..:||.:....  |.||:.|||:|.:::||||:::.......
Human   390 SKSAWLKDTVDPKLV--TLNHRIAALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLY 452

  Fly   433 ITTLGDRLASILFYASEVPQGGATVFPEINVTV 465
            ....|:|:|:.:.|.|.|..||||.|...|::|
Human   453 RMKSGNRVATFMIYLSSVEAGGATAFIYANLSV 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32201	NP_730346.2	P4Ha_N	36..165	CDD:285528	33/138 (24%)
		P4Hc	341..507	CDD:214780	42/133 (32%)
P4HA3	NP_001275677.1	P4Ha_N	58..159	CDD:285528	29/128 (23%)
		TPR_12	186..252	CDD:290160	18/79 (23%)
		P4Hc	356..>478	CDD:214780	39/124 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149278
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750