DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment PIP82 and Nkd2

DIOPT Version :10

Sequence 1:	NP_572487.3	Gene:	PIP82 / 31791	FlyBaseID:	FBgn0024943	Length:	1195	Species:	Drosophila melanogaster
Sequence 2:	NP_082462.3	Gene:	Nkd2 / 72293	MGIID:	1919543	Length:	461	Species:	Mus musculus

Alignment Length:	21	Identity:	14/21 - (66%)
Similarity:	18/21 - (85%)	Gaps:	0/21 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QQFQHYPHHQHHHHHHHHHIH 26
            |:.:|:.||:|||||||||.|
Mouse   439 QRHEHHHHHEHHHHHHHHHFH 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP82	NP_572487.3	None
Nkd2	NP_082462.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..106
		Interaction with DVL1, DVL2 and DVL3. /evidence=ECO:0000269\|PubMed:11356022	121..186
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..205
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	263..302
		Interaction with TGFA. /evidence=ECO:0000250	307..396
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..359
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	372..414
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	441..461		13/19 (68%)
Blue background indicates that the domain is not in the aligned region.

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