Protein Alignment CG32191 and ARSJ

DIOPT Version :10

• Sequence 1: NP_730304.2
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_078866.3
• Gene: ARSJ / 79642
• HGNCID: 26286
• Length: 599
• Species: Homo sapiens
• Alignment Length: 590
• Identity: 183/590 - (31%)
• Similarity: 281/590 - (47%)
• Gaps: 116/590 - (19%)

  Fly     3 GLSAFLLLLCL---------QRVKSDESAA---------------ARRPNIIIIMADDMGFDDVS 43
            |..|...:|||         |.::.:|..|               ..:|::|.|:|||.||.||.
Human    28 GALAGFWILCLLTYGYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFRDVG 92

  Fly    44 FRGGREFLTPNIDALAYHGRLLDRLYAPAMCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLN 108
            :.|. |..||.:|.||..|..|:..|...:|||||...::|:|.||||.||.:|...:|..|.|:
Human    93 YHGS-EIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLD 156

  Fly   109 ATLMPEIFKEAGYSTNLVGKWHLGFSRPEYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYS-- 171
            ...:|:..||.||||::||||||||.|.|..|||||||..||......||:        .:|.
Human   157 NATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYY--------THYKCD 213

  Fly   172 ----LGYDFRRNMELEC-RDRGVYVTDLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPL 231
                .|||...|..... .|.|:|.|.:.|...::::..| :..:|:||.:::.|.|:     ||
Human   214 SPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASH-NPTKPIFLYIAYQAVHS-----PL 272

  Fly   232 QAPEEEIQKFSYIKDPNRRKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNGA-PSVGMF 295
            |||....:.:..|.:.|||:||||:|.||:::..:..||.:.....|||:|:.||||. |:.|
Human   273 QAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAG-- 335

  Fly   296 SNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLK 360
               |||:||||.|.|.||||:|..|.:.|..|:.:|::.::.:::.||.|||...|:.::|..::
Human   336 ---GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDIQ 397

  Fly   361 LDGIDLWPELSGSADAPHVPREILHILD---------------DVWRL---SALQMGQWKYVNGT 407
            |||.|:|..:|....:|.|  :|||.:|               .:|..   ||:::..||.:.|.
Human   398 LDGYDIWETISEGLRSPRV--DILHNIDPIYTKAKNGSWAAGYGIWNTAIQSAIRVQHWKLLTGN 460

  Fly   408 TASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATSRALSRYDLRRLTQQRISLTRRLAAVRCGDL 472
            ..   |...:..:...:|.|                       .|...:||:|:...:.
Human   461 PG---YSDWVPPQSFSNLGP-----------------------NRWHNERITLSTGKSV------ 493

  Fly   473 QRSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQELRASASRPGNRASMPEADPTL 537
                      .|::|.:||.|:.:|  |.|:..::..|.||:.:...:|.........|.::|.|
Human   494 ----------WLFNITADPYERVDL--SNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRL 546

  Fly   538 HTCAW 542
            :...|
Human   547 NGGVW 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_730304.2	4-S	27..408	CDD:293753	152/406 (37%)
ARSJ	NP_078866.3	4-S	76..509	CDD:293753	165/498 (33%)
		DUF4976	<495..>533	CDD:419068	12/39 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	531..599		4/21 (19%)