DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32191 and Gns

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_083640.1	Gene:	Gns / 75612	MGIID:	1922862	Length:	544	Species:	Mus musculus

Alignment Length:	555	Identity:	128/555 - (23%)
Similarity:	205/555 - (36%)	Gaps:	160/555 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RGLSAFLLLL----CLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHG 62
            |.|.|.|||.    ||..|     .||||||:::::.||...:    .||...|......:...|
Mouse    15 RRLPALLLLPLLGGCLGLV-----GAARRPNVLLLLTDDQDAE----LGGMTPLKKTKALIGEKG 70

  Fly    63 RLLDRLYAP-AMCTPSRGALLSGRYPIHTGTQHFVISN-------EEPWALTLNATLMPEIFKE- 118
            ......|.| |:|.|||.::|:|:|| |   .|.|::|       .:.|.........|.|.|.
Mouse    71 MTFSSAYVPSALCCPSRASILTGKYP-H---NHHVVNNTLEGNCSSKAWQKIQEPYTFPAILKSV 131

  Fly   119 AGYSTNLVGKWHLGFSRP-----EYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSLGYDFRR 178
            .||.|...||:...:..|     |:.|      ..:.||.|    .::.||.        |::..
Mouse   132 CGYQTFFAGKYLNEYGAPDAGGLEHIP------LGWSYWYA----LEKNSKY--------YNYTL 178

  Fly   179 NMELECRDRGV-----YVTDLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEI 238
            ::..:.|..|.     |:||:| |.......|:....:|.|:|:|..|.|:     |..|..:..
Mouse   179 SINGKARKHGENYSVDYLTDVL-ANLSLDFLDYKSNSEPFFMMISTPAPHS-----PWTAAPQYQ 237

  Fly   239 QKFS----------------------------------YIKDPNRRKYAAMISKLDQSVGRIITA 269
            :.|.                                  ::.|..||::..::| :|..|.:::..
Mouse   238 KAFQNVIAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIRFLDDAFRRRWQTLLS-VDDLVEKLVKR 301

  Fly   270 LSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIF 334
            |.||.:|:|:.:.:.||||       .:|| .|.|...|...:|..::|...:...|::...:
Mouse   302 LDSTGELDNTYIFYTSDNG-------YHTG-QFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQT-- 356

  Fly   335 RQPLYVA--DWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWRLSAL- 396
             ..:.|:  |..||:...|..:|:.: ::||:.|.|.|.|..:.             .||...|
Mouse   357 -SKMLVSNIDLGPTILDLAGYDLNKT-QMDGMSLLPILKGDRNL-------------TWRSDVLV 406

  Fly   397 -QMGQWKYVNGTTA--------------------SGRYDSV--------LTYRELDDLDPRDSRY 432
             ..|:.:.|...|.                    :..|..|        |.|.|.||.:.....|
Mouse   407 EYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTLSSLWNLQYCEFDDQEVFVEVY 471

  Fly   433 AVT-----VRNSATS---RALSRYDLRRLTQQRIS 459
            .:|     :.|.|.|   ..|.:.:.|.:..|..|
Mouse   472 NITADPDQITNIAKSIDPELLGKMNYRLMMLQSCS 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	118/527 (22%)
		4-S	27..408	CDD:293753	98/437 (22%)
		DUF4976	<478..540	CDD:303608
Gns	NP_083640.1	AslA	35..496	CDD:225661	116/518 (22%)
Gns	NP_083640.1	G6S	38..487	CDD:293766	111/506 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847550
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740