Protein Alignment CG32191 and SGSH

DIOPT Version :10

• Sequence 1: NP_730304.2
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Alignment Length: 619
• Identity: 139/619 - (22%)
• Similarity: 214/619 - (34%)
• Gaps: 199/619 - (32%)

  Fly     6 AFLLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLY- 69
            |.||:|.|.|        ||..|.::::|||.||:..::... ...||::||||....|....:
Human    10 ALLLVLGLCR--------ARPRNALLLLADDGGFESGAYNNS-AIATPHLDALARRSLLFRNAFT 65

  Fly    70 APAMCTPSRGALL-------SGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVG 127
            :.:.|:|||.:||       :|.|.:|....||...::        ...:|.:..:||..|.::|
Human    66 SVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDK--------VRSLPLLLSQAGVRTGIIG 122

  Fly   128 KWHLGFSRPEYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELECRDRGVYVT 192
            |.|:|   ||   |...||:      ||.:  :..|.:.|.                  |.:...
Human   123 KKHVG---PE---TVYPFDF------AYTE--ENGSVLQVG------------------RNITRI 155

  Fly   193 DLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPL----------------QAPEEEIQKF 241
            .||   ..:.::...|:  |.||.::....|......|.                :.|:...|.:
Human   156 KLL---VRKFLQTQDDR--PFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAY 215

  Fly   242 SYIK------DPN----RRKYAAM---ISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVG 293
            ..:.      .||    |...||.   :.::||.||.::..|.....|.:::|||.||||.|
Human   216 DPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIP--- 277

  Fly   294 MFSNTGSNFPLRGQKNTPWEGGVRVAGAI----------WSSGLQARGSIFRQPLYVADW--LPT 346
                    || .|:.|..|.|   .|..:          |....:|..|:......:.||  :|.
Human   278 --------FP-SGRTNLYWPG---TAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPY 330

  Fly   347 LSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWRLSALQMGQWKYVNGTTASG 411
            .|.|  |....::.|.|..|.|.|....                         .|..|.|  :..
Human   331 PSYA--IFGSKTIHLTGRSLLPALEAEP-------------------------LWATVFG--SQS 366

  Fly   412 RYDSVLTY----------RELDDLD-----PRDSRYAVTVRNSATSRALSRYDLRRLTQQRISLT 461
            .::..::|          |.:.:|:     |.|..:.|    |.|.:.|              |.
Human   367 HHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYV----SPTFQDL--------------LN 413

  Fly   462 RRLAAVRCG---DLQRSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQELRASASR 523
            |..|....|   ||:........| |||...||.|..||....|.:.:|..||.::.:.:.....
Human   414 RTTAGQPTGWYKDLRHYYYRARWE-LYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHD 477

  Fly   524 PGNRASMPEADPTLHTCAWESF--EVLKPRIVPL 555
            |             ..||.:..  |.|.|:..||
Human   478 P-------------WVCAPDGVLEEKLSPQCQPL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_730304.2	4-S	27..408	CDD:293753	95/429 (22%)
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	123/556 (22%)