Protein Alignment CG32191 and SGSH

DIOPT Version :9

• Sequence 1: NP_001287102.1
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 138/611 - (22%)
• Similarity: 215/611 - (35%)
• Gaps: 183/611 - (29%)

  Fly     6 AFLLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLY- 69
            |.||:|.|.|        ||..|.::::|||.||:..::... ...||::||||....|....:
Human    10 ALLLVLGLCR--------ARPRNALLLLADDGGFESGAYNNS-AIATPHLDALARRSLLFRNAFT 65

  Fly    70 APAMCTPSRGALL-------SGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVG 127
            :.:.|:|||.:||       :|.|.:|....||...::        ...:|.:..:||..|.::|
Human    66 SVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDK--------VRSLPLLLSQAGVRTGIIG 122

  Fly   128 KWHLGFSRPEYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELECRDRGVYVT 192
            |.|:|   ||   |...||:      ||.:  :..|.:.|.                  |.:...
Human   123 KKHVG---PE---TVYPFDF------AYTE--ENGSVLQVG------------------RNITRI 155

  Fly   193 DLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPL----------------QAPEEEIQKF 241
            .||   ..:.::...|:  |.||.::....|......|.                :.|:...|.:
Human   156 KLL---VRKFLQTQDDR--PFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAY 215

  Fly   242 SYIK------DPN----RRKYAAM---ISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVG 293
            ..:.      .||    |...||.   :.::||.||.::..|.....|.:::|||.||||.|
Human   216 DPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIP--- 277

  Fly   294 MFSNTGSNFPLRGQKNTPWEGGVRVAGAI----------WSSGLQARGSIFRQPLYVADW--LPT 346
                    || .|:.|..|.|   .|..:          |....:|..|:......:.||  :|.
Human   278 --------FP-SGRTNLYWPG---TAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPY 330

  Fly   347 LSRA----ADIELDSSLKLDGID---LWPELSGSADAPHVPREILHILDDVWRLSALQMGQWKYV 404
            .|.|    ..|.|.....|..::   ||..:.||..  |      |.:...:.:.::|...::.|
Human   331 PSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQS--H------HEVTMSYPMRSVQHRHFRLV 387

  Fly   405 NGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATSRALSRYDLRRLTQQRISLTRRLAAVRC 469
            :.......:             |.|..:.|    |.|.:.|              |.|..|....
Human   388 HNLNFKMPF-------------PIDQDFYV----SPTFQDL--------------LNRTTAGQPT 421

  Fly   470 G---DLQRSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQELRASASRPGNRASMP 531
            |   ||:........| |||...||.|..||....|.:.:|..||.::.:.:.....|
Human   422 GWYKDLRHYYYRARWE-LYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDP------- 478

  Fly   532 EADPTLHTCAWESF--EVLKPRIVPL 555
                  ..||.:..  |.|.|:..||
Human   479 ------WVCAPDGVLEEKLSPQCQPL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	105/490 (21%)
		4-S	27..408	CDD:293753	97/436 (22%)
		DUF4976	<478..540	CDD:303608	14/61 (23%)
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	122/548 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810