DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32191 and arsg

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001352290.1	Gene:	arsg / 564790	ZFINID:	ZDB-GENE-060503-154	Length:	526	Species:	Danio rerio

Alignment Length:	564	Identity:	144/564 - (25%)
Similarity:	222/564 - (39%)	Gaps:	151/564 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KSDESAAARRPNIIIIMADDMGFDDVSF-RGGREFLTPNIDALAYHGRLLDRLYAPA-MCTPSRG 79
            |.|......|||.|||:|||:|:.|:.. |......||.:|:|...|:.....::|| .|:|||.
Zfish    25 KEDNPEGKERPNFIIILADDIGWGDLWLNRPDNSTPTPWLDSLMLKGKRFTDFHSPASTCSPSRA 89

  Fly    80 ALLSGRYPIHTGTQH-FVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPEYTPTRR 143
            ::|:||:.:..|..| |.:.:  ...|.||.|...::..:.||.|.::||||||.: ..|:|..|
Zfish    90 SILTGRHGLRNGVTHNFAVGS--VGGLPLNETTFAQLLHDEGYYTAMIGKWHLGHN-GSYSPVHR 151

  Fly   144 GFDYHFGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMEL-EC------------RDRGVYV-TDL 194
            ||||:.|              :|.:| .:|...:..::| .|            :..|.|. ..|
Zfish   152 GFDYYLG--------------IPYSN-DMGCTDKPGLDLPSCPPCVHSQYSINKKHEGCYTKVGL 201

  Fly   195 LTAEAERLIKDHAD----------------------KEQP--LFLMLSHLAA---H----TANED 228
            ...|.|::|:...|                      |:||  |::.|:|:..   |    ....:
Zfish   202 PLFENEKIIEQPLDTWSLKDRYATAAVQQIFTASVTKKQPFLLYVALAHMHVPLFHNTFLNVTTE 266

  Fly   229 DPLQAPEEEIQKFSYIKDPNRRKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNG----- 288
            ||                     |.|.:|.:|..||.|:.|| .|:||||:::.|..|||
Zfish   267 DP---------------------YTASLSDMDSLVGNIVQAL-ITEQLENTLIWFTGDNGPWEQK 309

  Fly   289 -------APSVGMF-SNTGSNFPLRGQKNTPWEGGVRVAGAI-WSSGLQARGSIFRQPLYVADWL 344
                   .|.||.: :|.|..    ..|.|.||||.||...: |...:: ..|.....|...|..
Zfish   310 CLFAGHVGPFVGRWQTNKGGG----SAKRTTWEGGHRVPTVVSWPKKIK-HNSSSDALLSGLDIF 369

  Fly   345 PTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILH----ILDDVWRLSALQMGQWK--Y 403
            ||:...|.::..|..:.||||:...|...::..|  ..::|    .......|..:::...|  |
Zfish   370 PTVLSLAGVKPPSDRRYDGIDITDVLLNDSETGH--ESLMHPNSGAAGQYGDLQTVRLKHHKAFY 432

  Fly   404 VNGTTA-----SG---RYDSVLTY------RELDDLDPRDSRYAVTVRNSATSRALSRYDLRRLT 454
            :.|.:.     ||   .:|..|.:      .|...|||....:              |..|:::.
Zfish   433 ITGGSVACDGESGPQQHHDPPLIFDLSQDEAEETPLDPESKEF--------------RSVLKQVE 483

  Fly   455 QQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQNNLV 498
            ::|.:|...:|..|......:..|..|.|        ||..|.|
Zfish   484 REREALLWDIATDRVSAADYTVIPSAEPC--------CEPQNPV 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	131/516 (25%)
		4-S	27..408	CDD:293753	120/448 (27%)
		DUF4976	<478..540	CDD:303608	7/21 (33%)
arsg	NP_001352290.1	ALP_like	34..469	CDD:329031	126/481 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840