Protein Alignment CG32191 and ARSB

DIOPT Version :10

• Sequence 1: NP_730304.2
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_000037.2
• Gene: ARSB / 411
• HGNCID: 714
• Length: 533
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 189/567 - (33%)
• Similarity: 285/567 - (50%)
• Gaps: 95/567 - (16%)

  Fly     8 LLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAPA 72
            ||||.|.......:.|:|.|:::.::|||:|::||.|.|.| ..||::||||..|.|||..|...
Human    26 LLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYTQP 89

  Fly    73 MCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPE 137
            :|||||..||:|||.|.||.||.:|...:|..:.|:..|:|::.|||||:|::|||||||..|.|
Human    90 LCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKE 154

  Fly   138 YTPTRRGFDYHFGYWGAYIDYF--QRRSKMPVANYS-LGYDFRRNMELECRDRGVYVTDLLTAEA 199
            ..|||||||.:|||.....||:  :|.:.:...|.: ...|||...|:....:.:|.|::.|..|
Human   155 CLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRA 219

  Fly   200 ERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNRRKYAAMISKLDQSVG 264
            ..||.:| ..|:||||.|:..:.|     :|||.|||.::.:.:|:|.||..||.|:|.:|::||
Human   220 IALITNH-PPEKPLFLYLALQSVH-----EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVG 278

  Fly   265 RIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQA 329
            .:..||.|:....|::.||.:|||..::.    .|:|:||||:|.:.||||||..|.:.|..|:.
Human   279 NVTAALKSSGLWNNTVFIFSTDNGGQTLA----GGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQ 339

  Fly   330 RGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILD------ 388
            :|...|:.::::||||||.:.|....:.:..|||.|:|..:|..:.:|.:  |:||.:|
Human   340 KGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRI--ELLHNIDPNFVDS 402

  Fly   389 ------------DVWRL-----------SALQMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDS 430
                        |...|           :|::.|.||.:.|....|.:            .|..|
Human   403 SPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYW------------FPPPS 455

  Fly   431 RYAVTVRNSATSRALSRYDLRRLTQQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQN 495
            :|.|:                                   ::..|..|.....|:||..||.|::
Human   456 QYNVS-----------------------------------EIPSSDPPTKTLWLFDIDRDPEERH 485

  Fly   496 NLVYSERHSDVLTALRRRVQELRASASRPGNRASMPEADPTLHTCAW 542
            :|  |..:..::|.|..|:|.....:......|..|..||.. |..|
Human   486 DL--SREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKA-TGVW 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_730304.2	4-S	27..408	CDD:293753	157/412 (38%)
ARSB	NP_000037.2	4-S	45..488	CDD:293753	171/504 (34%)