Protein Alignment CG32191 and ARSA

DIOPT Version :9

• Sequence 1: NP_001287102.1
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_016884289.1
• Gene: ARSA / 410
• HGNCID: 713
• Length: 547
• Species: Homo sapiens
• Alignment Length: 588
• Identity: 165/588 - (28%)
• Similarity: 235/588 - (39%)
• Gaps: 146/588 - (24%)

  Fly    22 AAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAP-AMCTPSRGALLSGR 85
            |.||.|||::|.|||:|:.|:...|.....|||:|.||..|......|.| ::|||||.|||:||
Human    18 AVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 82

  Fly    86 YPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPE--YTPTRRGFDYH 148
            .|:..|....|:.......|.|....:.|:....||.|.:.||||||.. ||  :.|..:||...
Human    83 LPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG-PEGAFLPPHQGFHRF 146

  Fly   149 FGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELEC----------RDRGVYVTDLLT------- 196
            .|     |.|  ...:.|..|            |.|          .|:|:....||.
Human   147 LG-----IPY--SHDQGPCQN------------LTCFPPATPCDGGCDQGLVPIPLLANLSVEAQ 192

  Fly   197 ------------AEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNR 249
                        |.|..|:.|...:::|.||   :.|:|..:      .|:...|.|:  :...|
Human   193 PPWLPGLEARYMAFAHDLMADAQRQDRPFFL---YYASHHTH------YPQFSGQSFA--ERSGR 246

  Fly   250 RKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEG 314
            ..:...:.:||.:||.::||:.....||.::|||.:||| |.....|..|.:..||..|.|.:||
Human   247 GPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNG-PETMRMSRGGCSGLLRCGKGTTYEG 310

  Fly   315 GVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHV 379
            |||.....:..|..|.| :..:.....|.||||:..|...| .::.|||.||.|.|.|:..:
Human   311 GVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLGTGKS--- 370

  Fly   380 PREILHIL----DDVWRLSALQMGQWK---YVNGTTASGRYDSVLTYRELDDL--DPRDSRYAVT 435
            ||:.|...    |:|..:.|::.|::|   :..|..:        .:....||  .||..|
Human   371 PRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGNPS--------PWIPPPDLLTPPRSPR---- 423

  Fly   436 VRNSATSRALSRYDLRRLTQQRISLTRRLAAVRCGDLQRS-------------CN---------- 477
                                   ||...||...|.:|..|             |:
Human   424 -----------------------SLAPPLALALCTELAPSPGSAHSDTTADPACHASSSLTAHEP 465

  Fly   478 PLLEECLYDILSDPCEQNNLV--YSERHSDVLTALRRRVQELRA---SASRPGNRASMPEADPTL 537
            ||    |||:..||.|..||:  .:....:||.|| :::|.|:|   :|...|........||.|
Human   466 PL----LYDLSKDPGENYNLLGGVAGATPEVLQAL-KQLQLLKAQLDAAVTFGPSQVARGEDPAL 525

  Fly   538 HTC 540
            ..|
Human   526 QIC 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	133/475 (28%)
		4-S	27..408	CDD:293753	126/419 (30%)
		DUF4976	<478..540	CDD:303608	22/66 (33%)
ARSA	XP_016884289.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157184
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.946395	Normalized mean entropy	S6897
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.690