Protein Alignment CG32191 and ARSA

DIOPT Version :10

• Sequence 1: NP_730304.2
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_000478.3
• Gene: ARSA / 410
• HGNCID: 713
• Length: 509
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 159/560 - (28%)
• Similarity: 227/560 - (40%)
• Gaps: 128/560 - (22%)

  Fly    22 AAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAP-AMCTPSRGALLSGR 85
            |.||.|||::|.|||:|:.|:...|.....|||:|.||..|......|.| ::|||||.|||:||
Human    18 AVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 82

  Fly    86 YPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPE--YTPTRRGFDYH 148
            .|:..|....|:.......|.|....:.|:....||.|.:.||||||.. ||  :.|..:||...
Human    83 LPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG-PEGAFLPPHQGFHRF 146

  Fly   149 FGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELEC----------RDRGVYVTDLLT------- 196
            .|     |.|  ...:.|..|            |.|          .|:|:....||.
Human   147 LG-----IPY--SHDQGPCQN------------LTCFPPATPCDGGCDQGLVPIPLLANLSVEAQ 192

  Fly   197 ------------AEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNR 249
                        |.|..|:.|...:::|.||   :.|:|..:      .|:...|.|:  :...|
Human   193 PPWLPGLEARYMAFAHDLMADAQRQDRPFFL---YYASHHTH------YPQFSGQSFA--ERSGR 246

  Fly   250 RKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEG 314
            ..:...:.:||.:||.::||:.....||.::|||.:||| |.....|..|.:..||..|.|.:||
Human   247 GPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNG-PETMRMSRGGCSGLLRCGKGTTYEG 310

  Fly   315 GVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHV 379
            |||.....:..|..|.| :..:.....|.||||:..|...| .::.|||.||.|.|.|:..:
Human   311 GVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLGTGKS--- 370

  Fly   380 PREILHIL----DDVWRLSALQMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSA 440
            ||:.|...    |:|..:.|::.|::|....|..|...|:.        .||     |....:|.
Human   371 PRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTT--------ADP-----ACHASSSL 422

  Fly   441 TSRALSRYDLRRLTQQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQNNLV--YSERH 503
            |:.                                 .|.|   |||:..||.|..||:  .:...
Human   423 TAH---------------------------------EPPL---LYDLSKDPGENYNLLGGVAGAT 451

  Fly   504 SDVLTALRRRVQELRA---SASRPGNRASMPEADPTLHTC 540
            .:||.|| :::|.|:|   :|...|........||.|..|
Human   452 PEVLQAL-KQLQLLKAQLDAAVTFGPSQVARGEDPALQIC 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_730304.2	4-S	27..408	CDD:293753	125/416 (30%)
ARSA	NP_000478.3	ARSA	22..505	CDD:293777	156/556 (28%)