DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32191 and CG7408

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001163462.1	Gene:	CG7408 / 39991	FlyBaseID:	FBgn0036765	Length:	585	Species:	Drosophila melanogaster

Alignment Length:	547	Identity:	261/547 - (47%)
Similarity:	355/547 - (64%)	Gaps:	18/547 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LSAFLLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRL 68
            |:.|:|.:.|   .:...|.:.:||||||||||:|||||||||...|||||||||||.|.:|:.|
  Fly    15 LTGFVLCIAL---SNGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNL 76

  Fly    69 YAPAMCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGF 133
            |...||||||.|||:|:|||:||.||:||.|::||.|.||.|.|.|||:|.||.|:|:||||||.
  Fly    77 YVAPMCTPSRAALLTGKYPINTGMQHYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGL 141

  Fly   134 SRPEYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELECRDRGVYVTDLLTAE 198
            |:..:|||.||||.|.||.|||:||:.:..:.....|: |:|||.:::......|.|||||||..
  Fly   142 SQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGYN-GHDFRDSLKSTHDHVGHYVTDLLTDA 205

  Fly   199 AERLIKDHADK--EQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNRRKYAAMISKLDQ 261
            |.:.|:||..|  .|||||:|:|||.|.||:|||:|||.||:.:|.||.:...|.||||:|:||:
  Fly   206 AVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDK 270

  Fly   262 SVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSG 326
            |||.:|.||:..:.|:|||::|.||||.|:.|..|.|.||:|||||||:||||.:|.:.||||:.
  Fly   271 SVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTE 335

  Fly   327 LQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILD-DV 390
            .:..||:::|.:|:.|.||||:.||.|..|.:|.|||::||..|....::  |.|||:|::| ||
  Fly   336 FERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYES--VEREIVHVIDEDV 398

  Fly   391 W--RLSALQMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATSRALSRYDLRRL 453
            .  .||..: |:||.::|||..|.||..|.:||..::|||...|...|||::....|.:..   .
  Fly   399 AEPHLSYTR-GKWKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWLQLQQVS---F 459

  Fly   454 TQQRISLTRRLAAVRCGDLQ---RSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQ 515
            .::.||..|..:.:.|.|..   :.|.||...||:||.:||||::||....::|.:...|..|:|
  Fly   460 GERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQ 524

  Fly   516 ELRASASRPGNRASMPEADPTLHTCAW 542
            :....|..|.|:...|..||..:...|
  Fly   525 QFAKQAHPPNNKPGDPNCDPRFYHNEW 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	227/439 (52%)
		4-S	27..408	CDD:293753	211/385 (55%)
		DUF4976	<478..540	CDD:303608	22/61 (36%)
CG7408	NP_001163462.1	AslA	31..425	CDD:225661	216/397 (54%)
CG7408	NP_001163462.1	4-S	35..423	CDD:293753	214/391 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468724
Domainoid	1	1.000	294	0.414	Domainoid score	I1467
eggNOG	1	0.900	-	-		E1_COG3119
Homologene	1	1.000	-	-		H44428
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2236
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm6503
orthoMCL	1	0.900	-	-		OOG6_100690
Panther	1	1.100	-	-	P	PTHR10342
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
	12	11.800