DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32191 and Arsk

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001041382.1	Gene:	Arsk / 365619	RGDID:	1310182	Length:	563	Species:	Rattus norvegicus

Alignment Length:	524	Identity:	118/524 - (22%)
Similarity:	187/524 - (35%)	Gaps:	154/524 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ARRPNIIIIMADDMGFDD-VSFRGGREFL-TPNIDALAYHGRLLDRLYAPA-MCTPSRGALLSGR 85
            |:.||::::.:|  .||. ::|:.|.:.: .|.|:.:...|......|..: :|.|||.|:.||.
  Rat    29 AQAPNVVLVASD--SFDGRLTFQPGSQVVKLPFINFMRARGTTFLNAYTNSPICCPSRAAMWSGL 91

  Fly    86 YPIHTGTQHFVISNEEPW----ALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPEYTPTRRGFD 146
            :...|          |.|    .|..|.|...::.::.||.|...||                .|
  Rat    92 FTHLT----------ESWNNFKGLDPNYTTWMDVMEKHGYQTQKFGK----------------LD 130

  Fly   147 YHFGY---------WGAYIDYFQRRSKMPVANYSLGYDFRRNMELECRDRGVYVTDLLTAEAERL 202
            |..|:         |...:.:..|:...|:.|.....:.||.|:.:.::     ||...|...::
  Rat   131 YSSGHHSISNRVEAWTRDVAFLLRQEGRPIINLIPDKNRRRVMDKDWQN-----TDKAIAWLRQV 190

  Fly   203 IKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEE--------------IQKFSY--IKDPN--- 248
                 :..:|..|.|.      .|...|..:|...              ::|.:|  ||.|.
  Rat   191 -----NSTKPFVLYLG------LNLPHPYPSPSSGENFGSSTFHTSLYWLEKVAYDAIKIPKWLA 244

  Fly   249 -----------------------------RRKYAAMISKLDQSVGRIITALSSTDQLENSIVIFY 284
                                         |..|.||.::.|..:|.||.||...:.|:.:|||:.
  Rat   245 LSEMHPVDYYSSYTKNCTGKFTENEIKNIRAFYYAMCAETDAMLGEIILALHKLNLLQKTIVIYT 309

  Fly   285 SDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQPLYVA--DWLPTL 347
            ||:|..::     ....|    .|.:.:|....|...:...|::|.   .:.|..|:  |..||:
  Rat   310 SDHGEMAM-----EHRQF----YKMSMYEASAHVPILMMGPGIKAN---LQVPSLVSLVDIYPTM 362

  Fly   348 SRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWRLS------------ALQMGQ 400
            ...|.|.|  .|.|.|..|.| ||.:..|......:.|   ..|.||            .|:.||
  Rat   363 LDIAGIPL--PLNLSGYSLLP-LSSNTSANDQAFRVHH---PPWILSEFHGCNANASTYMLRTGQ 421

  Fly   401 WKYVNGTTASGRYDSVLTYRELDD--LDPRDSRYAVTVRNSATSRALSRYDLRRLTQQRISLTRR 463
            |||:      ...|..|...:|.|  |||.:      :.|.||......|.|.:..:..|:..:.
  Rat   422 WKYI------AYSDGTLVQPQLFDLSLDPDE------LTNIATEFPEITYSLDQQLRSVINYPKV 474

  Fly   464 LAAV 467
            .|:|
  Rat   475 SASV 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	115/513 (22%)
		4-S	27..408	CDD:293753	102/458 (22%)
		DUF4976	<478..540	CDD:303608
Arsk	NP_001041382.1	ARSK	32..445	CDD:293781	108/480 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351134
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740