DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32191 and Arsa

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001030105.2	Gene:	Arsa / 315222	RGDID:	1310381	Length:	507	Species:	Rattus norvegicus

Alignment Length:	562	Identity:	151/562 - (26%)
Similarity:	233/562 - (41%)	Gaps:	124/562 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAP-AMCTPSRGALLSGR 85
            :.|..|||::|.|||:|:.|:...|.....|||:|.||..|......|.| ::|||||.|||:||
  Rat    16 STASPPNIMLIFADDLGYGDLGSYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80

  Fly    86 YPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPE--YTPTRRGFDYH 148
            .|:.:|....|:.......|.|....:.|:....||.|.:.||||||.. ||  :.|..:||...
  Rat    81 LPVRSGMYPGVLGPSSQGGLPLEEVTLAEVLAARGYLTGMAGKWHLGVG-PEGAFLPPHQGFHRF 144

  Fly   149 FGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELECR---DRGVYVTDL---LTAEAE------- 200
            .|     |.|  ...:.|..|.:.     ...::.|.   |:|:....|   ||.||:
  Rat   145 LG-----IPY--SHDQGPCQNLTC-----FPPDITCSGGCDQGLVPIPLLANLTVEAQPPWLPGL 197

  Fly   201 ---------RLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNRRKYAAMI 256
                     .|:.|...:.:|.||   :.|:|..:      .|:...|.|:  |...|..:...:
  Rat   198 EARYVSFSRDLMADAQRQGRPFFL---YYASHHTH------YPQFSGQSFT--KRSGRGPFGDSL 251

  Fly   257 SKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGA 321
            .:||.:||.::||:.....|..::|||.:||| |.:...|:.|.:..||..|.|.:|||||....
  Rat   252 MELDGAVGALMTAVGDLGLLGETLVIFTADNG-PELMRMSDGGCSGLLRCGKGTTFEGGVREPAL 315

  Fly   322 IWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAP------HVP 380
            ::..|....| :..:.....|.||||:......| .::.|||:|:.|.|.|:..:|      :.|
  Rat   316 VYWPGHITPG-VTHELASSLDLLPTLAALTGAPL-PNITLDGVDISPLLLGTGKSPRNSVFFYPP 378

  Fly   381 REILHILDDVWRLSALQMGQWK---YVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATS 442
                 ..|::..:.|::.|::|   :..|:..|             |..|..:.:|.
  Rat   379 -----FPDEIHGVFAVRNGKYKAHFFTQGSAHS-------------DTTPDPACHAA-------- 417

  Fly   443 RALSRYDLRRLTQQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQNNLVYS--ERHSD 505
                    .|||.....|                       |||:..||.|..||:.|  |...:
  Rat   418 --------NRLTAHEPPL-----------------------LYDLSKDPGENYNLLDSTEEVSPE 451

  Fly   506 VLTALRRRVQELRA--SASRPGNRASMPEA-DPTLHTCAWES 544
            .|.|| :.::.|:|  .|:...:.:.:.:. ||.|..|...|
  Rat   452 ALQAL-KHIELLKAEYDAAMTFSPSQIAKGEDPALQICCQPS 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	129/468 (28%)
		4-S	27..408	CDD:293753	121/414 (29%)
		DUF4976	<478..540	CDD:303608	19/66 (29%)
Arsa	NP_001030105.2	AslA	17..470	CDD:225661	146/537 (27%)
Arsa	NP_001030105.2	ALP_like	20..503	CDD:304875	150/558 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351137
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740