DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32191 and Gns

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	XP_006241458.1	Gene:	Gns / 299825	RGDID:	1305877	Length:	544	Species:	Rattus norvegicus

Alignment Length:	545	Identity:	131/545 - (24%)
Similarity:	205/545 - (37%)	Gaps:	144/545 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LSAFLLLL----CLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRL 64
            |.|.|||.    ||..|     .||||||:::::.||...:    .||...|......:...|..
  Rat    17 LPALLLLPLLSGCLGLV-----GAARRPNVLLLLTDDQDAE----LGGMTPLKKTKALIGEKGMT 72

  Fly    65 LDRLYAP-AMCTPSRGALLSGRYPIHTGTQHFVISN-------EEPWALTLNATLMPEIFK-EAG 120
            ....|.| |:|.|||.::|:|:|| |   .|.|::|       .:.|.........|.|.| ..|
  Rat    73 FSSAYVPSALCCPSRASILTGKYP-H---NHHVVNNTLEGNCSSKSWQKIQEPYTFPAILKLVCG 133

  Fly   121 YSTNLVGKWHLGFSRP-----EYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSLGYD--FRR 178
            |.|...||:...:..|     |:.|      ..:.||.|    .::.||  ..||:|..:  .||
  Rat   134 YQTFFAGKYLNEYGAPDAGGLEHVP------LGWSYWYA----LEKNSK--YYNYTLSINGKARR 186

  Fly   179 NMELECRDRGVYVTDLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDP--------LQAPE 235
            :.|....|   |:||:| |.......|:....:|.|:|:|..|.|:.....|        :.||.
  Rat   187 HGENYSVD---YLTDVL-ANLSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQKAFPNVIAPR 247

  Fly   236 EE---------------------IQKFSYIKDPNRRKYAAMISKLDQSVGRIITALSSTDQLENS 279
            .:                     .....::.|..||::..::| :|..|.:::..|.||.:|:|:
  Rat   248 NKNFNIHGTNKHWLIRQAKTPMTNSSIKFLDDAFRRRWQTLLS-VDDLVEKLVKRLDSTGELDNT 311

  Fly   280 IVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQPLYVA--D 342
            .:.:.||||       .:|| .|.|...|...:|..::|...:...|::...:   ..:.|:  |
  Rat   312 YIFYTSDNG-------YHTG-QFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQT---SKMLVSNID 365

  Fly   343 WLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWRLSAL--QMGQWKYVN 405
            ..||:...|..:|:.: ::||..|.|.|.|..:.             .||...|  ..|:.:.|.
  Rat   366 LGPTILDLAGYDLNKT-QMDGTSLLPILKGDGNL-------------TWRSDVLVEYQGEGRNVT 416

  Fly   406 GTTA--------------------SGRYDSV--------LTYRELDDLDPRDSRYAVT-----VR 437
            ..|.                    :..|..|        |.|.|.||.:.....|.:|     :.
  Rat   417 DPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTLSSMWNLQYCEFDDQEVFVEVYNITADPDQIT 481

  Fly   438 NSATS---RALSRYDLRRLTQQRIS 459
            |.|.|   ..|.:.:.|.:..|..|
  Rat   482 NIAKSIDPELLGKMNYRLMMLQSCS 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	122/519 (24%)
		4-S	27..408	CDD:293753	102/429 (24%)
		DUF4976	<478..540	CDD:303608
Gns	XP_006241458.1	G6S	38..487	CDD:293766	115/498 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740