DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32191 and sul-3

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001360719.1	Gene:	sul-3 / 183778	WormBaseID:	WBGene00006310	Length:	484	Species:	Caenorhabditis elegans

Alignment Length:	481	Identity:	153/481 - (31%)
Similarity:	233/481 - (48%)	Gaps:	54/481 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LSAFLLLLCLQR--VKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGR--L 64
            |..|||||....  ...|...|.::||::.|||||:||.||.::.. ...|||:..||:|..  |
Worm     6 LPTFLLLLLHNHGITGVDGQTATQKPNVLFIMADDLGFSDVDWKDS-TLHTPNLRHLAFHKNTAL 69

  Fly    65 LDRLYAPAMCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKW 129
            |...|...:|||:|.|.::|.||...|||:.|..:.||..:......:.|..::..|||.|||||
Worm    70 LSNSYVNQLCTPTRSAFMTGYYPFRVGTQNGVFLHMEPAGVPTMFPFLSENMRQLDYSTYLVGKW 134

  Fly   130 HLGFSRPEYTPTRRGFDYHFGYWGAYIDYF-------QRRSKMPVANYSLGY---------DFRR 178
            |||:.:.|:.||.|||||.:|::|....||       .|..|..|....|..         ||.:
Worm   135 HLGYCKKEFLPTNRGFDYFYGFYGPQTGYFNHSADQYHRELKRVVKGLDLFEEVGSGKSVPDFSQ 199

  Fly   179 NMELECRDRGVYVTDLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSY 243
            |        |||.|||.|..|..::.:| :..:|.|:.||:.|.|     .|||.|....:..:.
Worm   200 N--------GVYSTDLFTDVAMSVLDNH-NNSKPFFMFLSYQAVH-----PPLQVPRSFDKYCTR 250

  Fly   244 IKDPNRRKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTG-SNFPLRGQ 307
            :|:..||.|..|::.:|.::||::..|.:::..||::::|.||||..     :|.| ||.||||:
Worm   251 VKNRYRRIYCGMLTAMDFAIGRLVEYLKASNLYENTVIVFTSDNGGT-----ANFGASNAPLRGE 310

  Fly   308 KNTPWEGGVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSG 372
            |:|.||||.:....:.|......|.......:|.||..|:.....:|:||  ..|||:.|..|
Worm   311 KDTIWEGGTKTTTFVHSPMYIEEGGTRDMMFHVVDWHATILSITGLEIDS--YGDGINQWEYL-- 371

  Fly   373 SADAPHVPR-EILHILDDVWRLSALQMGQWKYVNGTT---ASGRYDSVLTYRELDDLDPRDSRYA 433
            ....|...| :.::.:|:  ..||::.|.:|.:.|..   .|...:....:|  ...||.:|:..
Worm   372 KTGRPKFRRFQFVYNIDN--HGSAIRDGDYKLIVGNVDRKMSKDKNRTRLFR--ITTDPTESKDI 432

  Fly   434 VTVRNSATSRALSRYD-LRRLTQQRI 458
            .........|.|::.| |::...:.:
Worm   433 ARSNPKIVRRLLAKLDQLKKFLHKNV 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	146/458 (32%)
		4-S	27..408	CDD:293753	136/400 (34%)
		DUF4976	<478..540	CDD:303608
sul-3	NP_001360719.1	4-S	31..433	CDD:293753	141/429 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165363
Domainoid	1	1.000	224	1.000	Domainoid score	I1449
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	269	1.000	Inparanoid score	I1835
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		otm14696
orthoMCL	1	0.900	-	-		OOG6_100690
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.800