DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32191 and arsb

DIOPT Version :9

Sequence 1:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	XP_021324609.1	Gene:	arsb / 100538007	ZFINID:	ZDB-GENE-111123-2	Length:	502	Species:	Danio rerio

Alignment Length:	533	Identity:	182/533 - (34%)
Similarity:	282/533 - (52%)	Gaps:	78/533 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAPA 72
            |.|||:..    |..:||.|::::|:|||:|::||.|.|. |..||::|.||..|..||..|...
Zfish     8 LCLLCVVL----ECVSARPPHVVLILADDLGWNDVGFHGS-EIKTPHLDRLAAQGVRLDNYYVQP 67

  Fly    73 MCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPE 137
            :|||||..|::|||.|.||.||.:|...:|:.:.|:..|:|::.:|.||.|::|||||||..:.:
Zfish    68 LCTPSRNQLMTGRYQIRTGLQHQIIWPCQPYCVPLDEKLLPQVLRERGYHTHMVGKWHLGMFQKD 132

  Fly   138 YTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSL---GYDFRRNMELECRDRGVYVTDLLTAEA 199
            ..||.|||...|||.....||:..:...|:|..::   ..|.|....:.....|.|.|:|||..|
Zfish   133 CLPTHRGFQSFFGYLTGSEDYYTHKRCSPIAPLNVTRCALDLRDGDAVALNYSGRYSTELLTERA 197

  Fly   200 ERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNRRKYAAMISKLDQSVG 264
            ..:|..|. .:|||||.::..|.|.     |||.|:..|..:|:|:||:||:||.|:|.:|::||
Zfish   198 THIITQHT-PDQPLFLYVALQAVHA-----PLQVPDHYIAPYSFIQDPHRRRYAGMVSAMDEAVG 256

  Fly   265 RIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSG--L 327
            .|...|..|...:|:::||.:|||    |.....|:|:||||:|.|.||||||  |..:.||  :
Zfish   257 NITHTLQETGLWDNTVLIFSTDNG----GQTLYGGNNWPLRGRKWTLWEGGVR--GVAFVSGPLI 315

  Fly   328 QARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWR 392
            :..|::.|:.::::|||||::..|....:.:..|||.|:|..:|....:|.|  |:||.:|.::.
Zfish   316 EKPGAVNRELIHISDWLPTIAGLAGASTNGTKPLDGFDVWQSISAGVASPRV--ELLHNIDPLYE 378

  Fly   393 LSALQMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATSRALSRYDLRRLTQQR 457
            .|:...|         ..|.:        |:|          ::.:|::|.:.|..|:.  .|..
Zfish   379 DSSPCPG---------GEGVF--------LED----------SLHSSSSSSSSSSSDVS--AQFN 414

  Fly   458 ISLTRRLAAVR------------C--------GDLQRSCNPLLEECLYDILSDPCEQNNLVYSER 502
            ||:.   ||:|            |        |....:..||.:..|:|:..||  :..|..|.:
Zfish   415 ISIH---AAIRHKNWKLLTGYPGCPLWIPPPGGRPVNASEPLKQVMLFDVEKDP--EERLEVSHQ 474

  Fly   503 HSDVLTALRRRVQ 515
            ..:|::.|.||:|
Zfish   475 RPEVVSFLLRRLQ 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	157/439 (36%)
		4-S	27..408	CDD:293753	147/385 (38%)
		DUF4976	<478..540	CDD:303608	13/38 (34%)
arsb	XP_021324609.1	4-S	23..472	CDD:293753	169/497 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592919
Domainoid	1	1.000	294	0.414	Domainoid score	I1467
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2236
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm6503
orthoMCL	1	0.900	-	-		OOG6_100690
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.800