DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otu and Otud3

DIOPT Version :9

Sequence 1:	NP_511089.2	Gene:	otu / 31789	FlyBaseID:	FBgn0003023	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001364018.1	Gene:	Otud3 / 73162	MGIID:	1920412	Length:	443	Species:	Mus musculus

Alignment Length:	397	Identity:	82/397 - (20%)
Similarity:	132/397 - (33%)	Gaps:	137/397 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QRPITSGSRQAPDP-----------YDQYLESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEI 59
            :|.:....|..|||           :...|::.||..:....|.:.|||.:.:|:......|.:.
Mouse    30 RRALAKERRNRPDPGGSGCEEEFVSFANQLQALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKH 94

  Fly    60 RLECVRFMTLKRRIFEKEIPGD--FDSYMQDMSKPKTYGTMTELRAMSCLYRRNVILYEPYN--- 119
            |.|.|.:|..:|..||..:..|  |:.::..:|||.|:.....:.|.:..::.||:::: .|
Mouse    95 RQETVDYMIRQREDFEPFVEDDIPFEKHVASLSKPGTFAGNDAIVAFARNHQLNVVIHQ-LNAPL 158

  Fly   120 ---MGTSVVFNR------RYAENF----RVFFNNENHFDSVYDVEYIE----------RAAICQS 161
               .||.....|      ||.|::    |:..|:|.....:.||...:          .|.:|..
Mouse   159 WQIRGTDKGSTRELHIAYRYGEHYDSVRRINDNSEAPAHLLTDVSEAQLLLLSGLQETGAELCPQ 223

  Fly   162 IAFKLLYQKLFKLP-------DVSFAVEI-MLHPHTFNWDRFNVEFDDKGYMVR----------I 208
            ::..   ..|..||       .::.||:. |||....|...   :...||..|:          :
Mouse   224 LSPS---GPLLSLPLREPAIQSIAKAVQFQMLHQDGANKKE---KMKTKGVDVKDGLRDDVEDAV 282

  Fly   209 H-------CTDGRVFKLDLPGDTNCILENYKLCNFH----------------------------- 237
            |       ||           |.|.|::|.:..|::
Mouse   283 HKVGSATGCT-----------DFNLIVQNLEAENYNIKSAITALLQVNQGTGNDAEENHEPGDRV 336

  Fly   238 --------------STNGNQSINARKGGRLEIKNQEERKASGSSGHEPNDLLPMCPN-------R 281
                          ..:|||   .|..||:|........|..|..|:..  ||...|       |
Mouse   337 KQRGPSREEAGSGRRLSGNQ---GRNEGRMETSEARASPAEESKAHKSQ--LPKVTNKQRREQQR 396

  Fly   282 LESCVRQ 288
            ||...||
Mouse   397 LEKKKRQ 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otu	NP_511089.2	OTU	37..>115	CDD:303090	22/79 (28%)
		TUDOR	335..392	CDD:197660
		TAF12	<446..>564	CDD:304643
Otud3	NP_001364018.1	OTU	70..182	CDD:388712	29/112 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835255
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840