DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otu and Otud1

DIOPT Version :9

Sequence 1:	NP_511089.2	Gene:	otu / 31789	FlyBaseID:	FBgn0003023	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_081991.1	Gene:	Otud1 / 71198	MGIID:	1918448	Length:	454	Species:	Mus musculus

Alignment Length:	140	Identity:	34/140 - (24%)
Similarity:	62/140 - (44%)	Gaps:	8/140 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DQYLESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEIRLECVRFMTLKRRIFEKEIPGDFDSY 85
            |:||..|..||.|...|.:.|:|.:::.:|..|.||.|:|.:.|.::......|...|.||...:
Mouse   274 DKYLRQRNKYRFHIIPDGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEF 338

  Fly    86 MQDMSKPKTYGTMTELRAMSCLYRRNVIL-----YEPYNMGTSVVF---NRRYAENFRVFFNNEN 142
            :...::...:....||.||..:...|:.|     .|...:.|.:.:   ......:..:.:.:..
Mouse   339 IIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNG 403

  Fly   143 HFDSVYDVEY 152
            |:|:|:|..|
Mouse   404 HYDAVFDHSY 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otu	NP_511089.2	OTU	37..>115	CDD:303090	20/82 (24%)
		TUDOR	335..392	CDD:197660
		TAF12	<446..>564	CDD:304643
Otud1	NP_081991.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..64
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..257
		Cys-loop. /evidence=ECO:0000250	287..293		1/5 (20%)
		OTU	288..405	CDD:280496	22/116 (19%)
		His-loop. /evidence=ECO:0000250	342..352		0/9 (0%)
		Variable-loop. /evidence=ECO:0000250	399..404		0/4 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2605
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700