DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otu and otud5a

DIOPT Version :9

Sequence 1:	NP_511089.2	Gene:	otu / 31789	FlyBaseID:	FBgn0003023	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001068578.1	Gene:	otud5a / 555459	ZFINID:	ZDB-GENE-030616-61	Length:	560	Species:	Danio rerio

Alignment Length:	214	Identity:	52/214 - (24%)
Similarity:	93/214 - (43%)	Gaps:	32/214 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QAPDP---------YDQYL-ESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEIRLECVRFMTL 69
            |:.||         :::.| |.:|...|....|.:.|||.:|:|:|..|.:|..:|..|:.::..
Zfish   187 QSEDPATVEQQEHWFEKALQEKKGFVIKKMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMK 251

  Fly    70 KRRIFEKEIPGDFDSYMQDMSKPKTYGTMTELRAMSCLYRRNVILYEPYNMGTSVV-----FNRR 129
            ....|...:..||.:|:....|...:|...|::||:.:|.|.|   |.|..||..:     .::.
Zfish   252 NADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPV---EVYQSGTEPINTFHGIHQN 313

  Fly   130 YAENFRVFFNNENHFDSVYDVEYIERAAICQSI---AFK------LLYQKLFKLPDVSFAVEIML 185
            ..|..||.::...|::||.:.   .:|.|...:   |||      .|.:...|..:.|:..:.||
Zfish   314 NDEPIRVSYHRNIHYNSVVNP---NKATIGVGLGLPAFKPGFADQSLMKNAIKTSEESWIEQQML 375

  Fly   186 H--PHTFNWDRFNVEFDDK 202
            .  ....:|:..|...:::
Zfish   376 EDKKRATDWEATNEAIEEQ 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otu	NP_511089.2	OTU	37..>115	CDD:303090	23/77 (30%)
		TUDOR	335..392	CDD:197660
		TAF12	<446..>564	CDD:304643
otud5a	NP_001068578.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..105
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	141..190		1/2 (50%)
		Cys-loop. /evidence=ECO:0000250	216..222		1/5 (20%)
		OTU	219..328	CDD:303090	30/111 (27%)
		Variable-loop. /evidence=ECO:0000250	271..281		2/9 (22%)
		His-loop. /evidence=ECO:0000250	322..327		0/4 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	411..496
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2605
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12419
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910