DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otu and Otud5

DIOPT Version :9

Sequence 1:	NP_511089.2	Gene:	otu / 31789	FlyBaseID:	FBgn0003023	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001277465.1	Gene:	Otud5 / 54644	MGIID:	1859615	Length:	567	Species:	Mus musculus

Alignment Length:	213	Identity:	51/213 - (23%)
Similarity:	94/213 - (44%)	Gaps:	30/213 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QAPDP---------YDQYL-ESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEIRLECVRFMTL 69
            :|.||         :::.| :.:|...|....|.:.|||.:|:|:|..|.:|..:|..|:.::..
Mouse   189 EAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMK 253

  Fly    70 KRRIFEKEIPGDFDSYMQDMSKPKTYGTMTELRAMSCLYRRNVILY----EPYNMGTSVVFNRRY 130
            ....|...:..||.:|:....|...:|...|::||:.:|.|.|.:|    ||.|  |....::..
Mouse   254 NADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYSTEPIN--TFHGIHQNE 316

  Fly   131 AENFRVFFNNENHFDSVYDVEYIERAAICQSI---AFK------LLYQKLFKLPDVSFAVEIMLH 186
            .|..||.::...|::||.:.   .:|.|...:   :||      .|.:...|..:.|:..:.||.
Mouse   317 DEPIRVSYHRNIHYNSVVNP---NKATIGVGLGLPSFKPGFAEQSLMKNAIKTSEESWIEQQMLE 378

  Fly   187 --PHTFNWDRFNVEFDDK 202
              ....:|:..|...:::
Mouse   379 DKKRATDWEATNEAIEEQ 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otu	NP_511089.2	OTU	37..>115	CDD:303090	23/77 (30%)
		TUDOR	335..392	CDD:197660
		TAF12	<446..>564	CDD:304643
Otud5	NP_001277465.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..117
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..175
		Cys-loop. /evidence=ECO:0000250	218..224		1/5 (20%)
		OTU	221..332	CDD:388712	32/112 (29%)
		Variable-loop. /evidence=ECO:0000250	273..283		2/9 (22%)
		His-loop. /evidence=ECO:0000250	324..329		0/4 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	413..499
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2605
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4984
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12419
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860