DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otu and Otud6a

DIOPT Version :9

Sequence 1:	NP_511089.2	Gene:	otu / 31789	FlyBaseID:	FBgn0003023	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001156663.1	Gene:	Otud6a / 408193	MGIID:	3644685	Length:	290	Species:	Mus musculus

Alignment Length:	168	Identity:	34/168 - (20%)
Similarity:	66/168 - (39%)	Gaps:	37/168 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ITSGSRQAPDPYDQYLESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEIRLECVRFMT---LK 70
            :.:..|:..:.....|.::.|..|....|...::|.|.:|      |.:.:.:|.:|:.|   ::
Mouse   122 LAANRREEEEKVAAILGAKNLEMKTIPADGHCMYRAIQDQ------LVFSVTIESLRYRTAYYMR 180

  Fly    71 RRI------FEKEIPG------DFDSYMQDMSKPKTYGTMTELRAMSCLYRR----------NVI 113
            :.|      |.:...|      ||..|..|:....::|...||||:|.:.:.          .::
Mouse   181 KHIDDFLPFFTEPEAGNFYTREDFLRYCDDIVHNASWGGQLELRALSHVLQTPIEVVQANSPTIV 245

  Fly   114 LYEPYNMGTSVVFNRRYAENFRVFFNNENHFDSVYDVE 151
            :.|.|......:....||.:|      ..|::||..:|
Mouse   246 IGEEYTRKPVTLVYLHYACDF------GEHYNSVKPIE 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otu	NP_511089.2	OTU	37..>115	CDD:303090	21/102 (21%)
		TUDOR	335..392	CDD:197660
		TAF12	<446..>564	CDD:304643
Otud6a	NP_001156663.1	COG5539	5..272	CDD:227826	31/161 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..117
		Cys-loop. /evidence=ECO:0000250	147..153		1/5 (20%)
		OTU	148..270	CDD:280496	26/133 (20%)
		Variable-loop. /evidence=ECO:0000250	211..221		1/9 (11%)
		His-loop. /evidence=ECO:0000250	259..269		3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835259
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840