DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)72Dp and ggh

DIOPT Version :9

Sequence 1:	NP_730119.1	Gene:	l(3)72Dp / 317887	FlyBaseID:	FBgn0263607	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_998487.1	Gene:	ggh / 406624	ZFINID:	ZDB-GENE-040426-2615	Length:	312	Species:	Danio rerio

Alignment Length:	318	Identity:	133/318 - (41%)
Similarity:	195/318 - (61%)	Gaps:	28/318 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SISLLIFIGALLAASEAGISSPIIGVLTQEVYVDGLISRHFD---NKTSYIAASYVKYLEGAGAR 66
            ::|:..| |.|:..:|    .||||||.|:|         ||   ::.|||||||||:||.||||
Zfish    15 AVSIYNF-GPLIKTNE----RPIIGVLAQDV---------FDPKPDRNSYIAASYVKFLESAGAR 65

  Fly    67 VVPIWIGRNRSYYDDLMRKINGVLLPGGATWFNQSNGYADAGEHLIHLAIELNDQGVFMPVWGTC 131
            |||:.|.::...|..|.:.|||||.|||.... :|:||:.|......||:|.|..|.:.||||||
Zfish    66 VVPVMINKSEDEYSRLFKSINGVLFPGGGVSL-ESSGYSKAAGIFYRLALEANSNGDYFPVWGTC 129

  Fly   132 LGMELLVYKLANE--TEHRINCEATGMAVPMEFKEDYKKSRLFASITDDVVDTMVKENVTYHWHQ 194
            ||.|||....:.|  ..|   ...:|:|:|::|.||.|.||||....::::.::..|.:|.:.||
Zfish   130 LGFELLTLLTSGELLLSH---TNTSGIALPLDFTEDVKGSRLFKEFPEELMKSLATEPLTENSHQ 191

  Fly   195 FCYTEKDFERD-LLNETWRVMSLNHD-WNGVEFISTVEHIKYPFYGVQFHPEKPLYEFTKTSIPH 257
            :..|.::|..: .|.:.:||:|.|.| :|  :|:||:|...:|.|..|:||||..:|:|:..|||
Zfish   192 WSITTENFTANKKLKKFYRVLSTNTDGYN--KFVSTMEAYDFPIYATQWHPEKNAFEWTRPYIPH 254

  Fly   258 TAAAVLSGQFFADFFVSEARESNQSFSNATEQARTLIYNYKPEYTSILGSSYIQQYLF 315
            |.:|:.:..:.|:|||:|||::..||::..|:.:.||||||||||.| .|::.|.|.|
Zfish   255 TPSAIKTTFYMANFFVNEARKNLHSFASTEEEEKALIYNYKPEYTGI-QSAFEQTYFF 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)72Dp	NP_730119.1	Peptidase_C26	26..244	CDD:285023	93/224 (42%)
l(3)72Dp	NP_730119.1	GATase1_Glutamyl_Hydrolase	28..303	CDD:153218	120/281 (43%)
ggh	NP_998487.1	GATase1_Glutamyl_Hydrolase	33..300	CDD:153218	120/281 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590432
Domainoid	1	1.000	161	1.000	Domainoid score	I3976
eggNOG	1	0.900	-	-		E1_KOG1559
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2881
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3479
OMA	1	1.010	-	-		QHG54943
OrthoDB	1	1.010	-	-		D539287at33208
OrthoFinder	1	1.000	-	-		FOG0002965
OrthoInspector	1	1.000	-	-		otm25109
orthoMCL	1	0.900	-	-		OOG6_101559
Panther	1	1.100	-	-	LDO	PTHR11315
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5199
SonicParanoid	1	1.000	-	-		X1961
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800