DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nxf3 and nxf4

DIOPT Version :9

Sequence 1:	NP_001287064.2	Gene:	Nxf3 / 317878	FlyBaseID:	FBgn0263232	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_731156.1	Gene:	nxf4 / 40884	FlyBaseID:	FBgn0051501	Length:	301	Species:	Drosophila melanogaster

Alignment Length:	239	Identity:	56/239 - (23%)
Similarity:	104/239 - (43%)	Gaps:	29/239 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 TVTGWSTVNI-ANCAGVSNSSIFVALKWVMMPIKVEIFNFKRSG-----PEDNMARGQFLLDNLL 133
            ::.||..|.| :....::.:.:...::.::.|:|:.. .:|.:|     .||:.|...|.:|:..
  Fly    39 SIYGWYRVLIYSTDRRLTFNRVLRRIRCILTPLKINP-RYKHTGGEQDTAEDSWALFTFFVDSYD 102

  Fly   134 SANRLKRLQEEVAVINTCQKIEVRVTPGLPK----SMMCAQITDEFTTAIQEALRSRYEVDSRTL 194
            .|:.|.|   ...|.|   :|.::|:..:||    |::...:|        ..|..||:...|:|
  Fly   103 VASALFR---RGWVDN---QIWLKVSDRMPKIWINSILRLHLT--------MVLLDRYDPVERSL 153

  Fly   195 DLSRFHASPELSLHFCPLHMVKLLETVLVLSNHLFPHVTSLVLSNNYLCSLKAFAGNSQSFASLE 259
            ||:.|:....|...|..|.....:.|||.:.:...|.:..|:|..|:|.:|..|....:.|..|.
  Fly   154 DLTLFYKDKALCGEFFALAESNCMSTVLGIVDREMPELERLILDGNHLTNLWVFRKVERRFPRLH 218

  Fly   260 RLDISANRIQDLGELNYINKLSCKTIFLAGN----GLAKLSVDV 299
            .:.:..|.|:::..|..:..|....:.|..|    |..|..:|:
  Fly   219 SISLKHNDIENIYSLRNLQFLPLAELNLLDNPLPAGYEKEVLDI 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nxf3	NP_001287064.2	leucine-rich repeat	191..231	CDD:275382	11/39 (28%)
		PPP1R42	<192..296	CDD:411060	28/107 (26%)
		leucine-rich repeat	232..257	CDD:275382	7/24 (29%)
		leucine-rich repeat	258..281	CDD:275382	4/22 (18%)
		NTF2_like	338..489	CDD:415585
nxf4	NP_731156.1	leucine-rich repeat	150..190	CDD:275382	11/39 (28%)
		LRR_4	189..235	CDD:289563	12/45 (27%)
		leucine-rich repeat	191..216	CDD:275382	7/24 (29%)
		leucine-rich repeat	217..240	CDD:275382	4/22 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840