Protein Alignment Nxf3 and sbr

DIOPT Version :10

• Sequence 1: NP_729938.2
• Gene: Nxf3 / 317878
• FlyBaseID: FBgn0263232
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: XP_307993.6
• Gene: sbr / 1269364
• VectorBaseID: AGAMI1_000971
• Length: 662
• Species: Anopheles gambiae
• Alignment Length: 612
• Identity: 148/612 - (24%)
• Similarity: 254/612 - (41%)
• Gaps: 120/612 - (19%)

  Fly    18 QNFKKHVNSQSPL--------------DDLRKNLNEKSKIREYVQELIGNEQQMGSVLDTISSTE 68
            :||.:...|.||:              .:.||.|...:...| |:...||:.:...:|.:|..
Mosquito   107 RNFDRQRRSGSPIPRGVPRGGGGGGGGGNQRKKLLPNAPWYE-VRIPYGNKYEKEFILRSIQQ-- 168

  Fly    69 EDHRVATVTGWSTVNIANCAGVSNSSIFVALKWVMMPIKVEIFNFKRSGPEDNMARGQFLLDNLL 133
                  .:|....:.:...|..|.:..||                     ||..|     .|.::
Mosquito   169 ------AITPQMFIPLYYKANESGAVFFV---------------------EDFQA-----ADAIM 201

  Fly   134 SANRLKRLQEEVAVINTCQKIEVRVTPGLPKSMMCAQITDEFTTAIQEALRSRYEVDSRTLDLSR 198
            .|||..:..:...:|     :.||..|  |.:    |:.::....:::|:..||...::.|||.:
Mosquito   202 RANRSIQTPDGRRMI-----LVVRNNP--PPT----QVNEQLKMRMKQAMVKRYNPQTKGLDLQK 255

  Fly   199 FHASPELSLHFCPLHMVK-LLETVLVLSNHLFPHVTSLVLSNNYLCSLKAFAGNSQSFASLERLD 262
            |||.|:||..||.|...: :|..:.:::.|: |.:.:|.|:.|.|..|......:.....|:.|.
Mosquito   256 FHADPDLSDIFCALFRPQIMLAAIDIIAEHI-PEIEALNLNENKLYMLDHLKSMTTKMPHLKVLY 319

  Fly   263 ISANRIQDLGELNYINKLSCKTIFLAGNGLAK------LSVDVIRKMLPQLKNVHGCVQLGEST- 320
            ::.|||..|..|:.:..|....:.|..|.|.|      ..|..:||..|::      ::|.:..
Mosquito   320 MARNRIPYLHSLDSLKGLKLLELNLLENPLCKHFDDNTAYVSEVRKRFPKV------IKLDDIVL 378

  Fly   321 ---------EAVDNIPKSQQLQGGGTNGLKFCQDFISSYYTFFDDTEERFKLKKYYDDQAMFSLS 376
                     |....:|:::......|:|....:.|:..|:|.: |::.|..|.:.|.:.|||||:
Mosquito   379 PPPISFDVPEDDTKLPEAKASFLCDTSGADLVRQFLEQYFTIY-DSDNRQPLLEAYHEHAMFSLT 442

  Fly   377 V--PVQLN------YVYGYKLYNRNQKRQHSSFAQNAKLQVGRAALLLALSRLPLMHTDLENVGL 433
            |  ..|.|      |:.|    :||.|.:....::...|:.||..::..||.||....||.:..:
Mosquito   443 VNTTYQSNQQKLGAYISG----SRNIKHKTDLDSRCRFLKQGRLQVVSHLSSLPPTKHDLTSFAV 503

  Fly   434 DIQVFTSSLRIFTLTGYFKEI--SSDTLEPRRFQRTFVLQTSNSPGWLITNDMLCITSTMPDPKK 496
            |:.:||..:...|:||.|||.  |.:..:.|.||||.|:..||. |:.|.|:|:.: :|:...::
Mosquito   504 DLTLFTPHMLQLTVTGVFKERKGSGNMEQIRSFQRTLVIVPSNG-GFCIRNEMMHV-NTVTRAQE 566

  Fly   497 TIKFKPETNMI-------NTDPSVEKINKPAVTV-LDRKSKEDVQISRPLSGKELNPLNKAVQKM 553
            ...||...|.:       :..|:|..:...|.|| |.......:|:.:.||.:  ..:|....|.
Mosquito   567 NKAFKGAENGMPQQQAAPSAAPTVPAVVGVAATVPLVPDDNTKLQMIQALSVQ--TNMNAEWSKR 629

  Fly   554 SLSQVD-HLPSENF--------NDMPP 571
            .|.:.: ..|...|        |.:||
Mosquito   630 CLEETNWDYPRAEFAFAELHKQNRIPP 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nxf3	NP_729938.2	leucine-rich repeat	191..231	CDD:275382	14/40 (35%)
		LRR	<229..>300	CDD:443914	19/76 (25%)
		leucine-rich repeat	232..257	CDD:275382	5/24 (21%)
		leucine-rich repeat	258..281	CDD:275382	7/22 (32%)
		NTF2_like	338..489	CDD:471850	52/160 (33%)
sbr	XP_307993.6	None