DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32121 and CG6765

DIOPT Version :9

Sequence 1:	NP_001097599.1	Gene:	CG32121 / 317867	FlyBaseID:	FBgn0052121	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	773	Identity:	161/773 - (20%)
Similarity:	256/773 - (33%)	Gaps:	283/773 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 QQFCLRWHNHQTSLLSTLPILLDQSHLTDVTISAEGRQ-----------LRAHRVVLSACSSFFM 81
            :.:.|:|.:|.|.|.|::..|.......||.:.:....           :.||:.:|||.|.||.
  Fly     4 ENYHLKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILSASSQFFA 68

  Fly    82 DIFRALEASNHP-----VIIIPGASFGAIVSLLTFMYSGEVNVYEEQIPMLLNLAETLGIKGLAD 141
            .:|.....:| |     |::.|..|..||..|:.:|||||..|..:.:..:|...|.|.|:||..
  Fly    69 TMFETAPITN-PNGVLYVVLPPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILKIRGLCR 132

  Fly   142 VQNNNLPKTARSGGGSYMDTTNEKSS------EFERPTTPSPTPTPTLTPSHTPTPSHSLPLPQL 200
            ..::|     ..|.||.:.||:...|      ..|..|......|.|..|...|.|..::
  Fly   133 TSSSN-----GGGSGSVVTTTHHPHSLAGHLHPREASTMYMSNGTRTALPPPPPPPQSTM----- 187

  Fly   201 PSAALNTPLLANKLGSVNSSGMGTTPLENLFKSLQFYPSLLPQPLNFSQTALNKTTELLAKYQQQ 265
             ||.|...|.|:|.|.                |.:|  :|....|:...:.||....     |||
  Fly   188 -SAQLQGDLYASKPGG----------------STRF--ALDHHHLSSHHSHLNHHNP-----QQQ 228

  Fly   266 CQLYQSGMQEDQLETDCFGSKRLKGDSPPKELRRLEKSLLKNPKSSSTTN----SSSSK------ 320
            .:    |:          |:..:..|||         .::|:||.::.|.    :||||
  Fly   229 FR----GL----------GASVMPKDSP---------VIIKSPKLAAHTGLLTVASSSKLGISVN 270

  Fly   321 -----SPQE--C----------SNPNPIVATSPV----------TLAPPTMAHFSPQLPV----- 353
                 .|::  |          |:|.|...|:..          :.|||:.       |:
  Fly   271 KEVAIDPEDKCCFAAPGQLESQSHPPPPTTTTTTVGGGGGSVGGSGAPPSQ-------PISICTE 328

  Fly   354 VKCSSASYPSALGQGQLYSS--------------------------------------KPPLYS- 379
            |.|||....:..|..|..::                                      :.|.:.
  Fly   329 VGCSSCPLTAGPGADQAETTLRRTEYEEQALRERNEVGLVFERRLRRESACERSRDYYEAPHFEH 393

  Fly   380 ------AAVTPTAAQQAAQMH----HHPQPGPSPYISAEDHAKLQLHIE--QYQREAAAAAAAAA 432
                  ||..|...|||...|    .||            |..|.:..|  .:......|::|:.
  Fly   394 VVSSRLAATPPPPPQQAPPSHPPTLRHP------------HNFLTIKQEPTDWSNNPPNASSASN 446

  Fly   433 GG----MALVSAKS----EPNLLSLSADRDKSLATA-----PIKPPSNSKLYATCFICHKQLSNQ 484
            ..    :.|.|.|.    :.:.:.|..:||:...:.     .::..:|.|....|.||.|...:.
  Fly   447 NNNLEELPLASPKQPLDFKMSAVKLEVNRDRGTPSEESEEHTLRDYNNFKQLLVCEICQKSFEDT 511

  Fly   485 YNLRVHLETH---------QNVRYACNVCSHVSRSKD-ALRKHVSYRHPGAPSPCENEARRKRVS 539
            ..|..||.||         :|:..:....|..|.|.: |||...:|    .|.      :|:|||
  Fly   512 KMLVRHLGTHAGDPTGGTERNLLPSSASGSTTSASSNLALRSVKTY----VPK------KRRRVS 566

  Fly   540 K---------------LAATTVPTST---------------------------------PMSMSA 556
            :               |.:|:..|..                                 |.:.|:
  Fly   567 QQENNMDHDHVTLLCDLCSTSFDTPAEWVRHMNSQHTEIELAMFNSKKDGEQKGQQPPPPPATSS 631

  Fly   557 SHTVTSGDVGPA-PATTLGCSGQEARNPYLFLPNQFQMAAAAAAVAVAESSPASGQPS 613
            |.||::..:.|. |::|      ..|:.:..:.::.   :.:.|||...|..||..|:
  Fly   632 SSTVSNSQMQPKYPSST------ATRSTHSLMLHKM---SNSDAVATTTSPGASTSPN 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32121	NP_001097599.1	BTB	48..142	CDD:279045	32/109 (29%)
		BTB	56..149	CDD:197585	32/108 (30%)
		C2H2 Zn finger	474..494	CDD:275370	7/19 (37%)
		C2H2 Zn finger	501..518	CDD:275370	6/17 (35%)
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	32/108 (30%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	27/77 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451906
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940