DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32112 and Abhd18

DIOPT Version :9

Sequence 1:	NP_001261779.1	Gene:	CG32112 / 317860	FlyBaseID:	FBgn0052112	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001020210.2	Gene:	Abhd18 / 499602	RGDID:	1563987	Length:	464	Species:	Rattus norvegicus

Alignment Length:	508	Identity:	228/508 - (44%)
Similarity:	313/508 - (61%)	Gaps:	71/508 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SKLDSIYRRMLITRFFEKGWGKPENLRKVFQFRKVISSRESCFKLVPRDYPVEITKKEIGAESTL 67
            ||||.:|||:|:|:.|.:|||:||:|:::|:|||:|.:||.|..||..||||.|.|.|..::..:
  Rat     4 SKLDILYRRLLLTKLFIRGWGRPEDLKRLFEFRKMIGNRERCQNLVSSDYPVHIDKVEEQSDCKI 68

  Fly    68 IEGQFKTPMELHMPGVVPEESQQAHFQLLIPNKWKNEKHKPICIHLAGTGDHFFWRRRNFIAKPL 132
            ::|.|.:||..::||::|.||..|.||.::|.:| |.:::|:||||||||||.:||||..:|:|:
  Rat    69 LDGHFVSPMAHYVPGIMPIESVIARFQFIVPKEW-NSRYRPVCIHLAGTGDHHYWRRRTLMARPM 132

  Fly   133 LKDANIGSIILENPFYGLRKPNNQTRSNLHNVSDIFVMGGCLILECLVLFHWCERNGFGPLGVTG 197
            :|:|.:.|::||||:||.|||.:|.||:|.||||:|||||.||||...|.||.||.|:||||:||
  Rat   133 IKEARMASLLLENPYYGCRKPKDQVRSSLKNVSDLFVMGGALILESAALLHWLEREGYGPLGMTG 197

  Fly   198 LSMGGHMASLAATNWPKPLVLVPCLSWSTASAVFTTGVMSQSINWDMLETQYFSDGQYRERLSKM 262
            :||||||||||.:|||||:.|:|||||||||.||||||:|:||||..||.||::...|.|.:..|
  Rat   198 ISMGGHMASLAVSNWPKPMPLIPCLSWSTASGVFTTGVLSKSINWRELEKQYYTQTVYEEEIIHM 262

  Fly   263 VTVI-DDAFSAGQSFIQNFNQSLQELKEDISDTRKIHATENSNTCGDKYETQGICPQEDSSIFLS 326
            :... .|:|..|..|:::|..:                                   ||
  Rat   263 LEYCGTDSFKMGHEFMKHFPSN-----------------------------------ED------ 286

  Fly   327 KSLKNTKLDSENLTIDAKDALSQKVAIETEETSKDSGSTLTNLMKFILPLSAQSKTDKIDITKT- 390
             .|.|..|.|..|.:|.:|.:......|...:.|.|.|..:....    |...:|.::::.|.|
  Rat   287 -KLTNLNLVSRTLNLDMRDQVVSPKHAECHHSGKASISATSKGQL----LQDTAKVERLNQTLTT 346

  Fly   391 ----------------------NWWEREALQFMRGMMDECTHLKNFSVPFDTSLIIAVCAKDDAY 433
                                  :..::|:|.||:|:||||||:.|||||.|.||||.|.||:|||
  Rat   347 NKSCFASYNPQSLHLLSREQRRSNLQKESLIFMKGVMDECTHVANFSVPVDPSLIIVVQAKEDAY 411

  Fly   434 VPREGCSSLEEIWPGAEVRYLDAGHVSAYVLHQKLFRSCIIEAFERAKKIYEN 486
            :||.|..||:|||||.|:|||:.||:|||:..|.|||..|.:||||....|.|
  Rat   412 IPRTGVRSLQEIWPGCEIRYLEGGHISAYLFKQGLFRQAIYDAFERFLHKYAN 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32112	NP_001261779.1	DUF2048	15..479	CDD:286795	216/487 (44%)
Abhd18	NP_001020210.2	DUF2048	16..457	CDD:286795	216/487 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349538
Domainoid	1	1.000	424	1.000	Domainoid score	I594
eggNOG	1	0.900	-	-		E1_KOG1551
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H105457
Inparanoid	1	1.050	443	1.000	Inparanoid score	I1596
OMA	1	1.010	-	-		QHG60068
OrthoDB	1	1.010	-	-		D1294532at2759
OrthoFinder	1	1.000	-	-		FOG0005846
OrthoInspector	1	1.000	-	-		oto97025
orthoMCL	1	0.900	-	-		OOG6_105322
Panther	1	1.100	-	-	LDO	PTHR13617
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4239
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810