DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32110 and Senp7

DIOPT Version :9

Sequence 1:	NP_729837.1	Gene:	CG32110 / 317858	FlyBaseID:	FBgn0052110	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_079759.2	Gene:	Senp7 / 66315	MGIID:	1913565	Length:	1037	Species:	Mus musculus

Alignment Length:	452	Identity:	92/452 - (20%)
Similarity:	160/452 - (35%)	Gaps:	141/452 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ENFQEQEEDVVMAVQEKLKFFRKLTSNGPAVPTPLKVVEKEDIGHKEIPKVVKKVDRKTKL---- 98
            ::.|.|.|:.:::.|.|...|..|..|.       .:.::|::..|:|...:...:....|
Mouse   587 QDIQTQLENPMLSQQSKANEFIFLELNS-------SISQREELKLKDIMMEISTKNGNLHLSCPL 644

  Fly    99 --LQAIPAVFKHSHNRRFRRSLFLRSNYIEQFRRWTDQKNKLNRKRLNEAHQLCLKAKHERIACE 161
              :||:|              ||                ..|:.:.::..|.....|.....|..
Mouse   645 PWVQALP--------------LF----------------QDLSPQEISFLHYYYASASALPTAAG 679

  Fly   162 IDRYKKLI--------LKQSVHVIEDIRISSELIPLTKEHHDRLMEL-SKYPLQQVIV-----AK 212
            .|..||.:        :|.:...:.........:.:|....:...|: :..|:|::||     .|
Mouse   680 ADMKKKSVSQPSNSDTIKPTYTFLHKQSSGCYSLSITSSPEEEWQEVRNTGPVQKLIVYPPPPTK 744

  Fly   213 FNLDICGSDIKILTSGGWLNDKIINFYMN-LLVERSEKRPGTVPSVYAMSTFFVPRL-------- 268
            ..|.:...|::.|..|.:|||.||:||:. ||:|::...  .|...:..|:||...|
Mouse   745 GGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDE--LVERSHIFSSFFYKCLTRKENNLT 807

  Fly   269 --------LQSGFDGVKRWTRKVDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNS------ 319
                    .|.....|:.|||.:::|:.|.|.|||::. .||.|.:|..|......|..
Mouse   808 EDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNES-SHWYLAVICFPWLEEAVYEDCPQTVS 871

  Fly   320 ---RGR----------GDP--------------------------------------------NL 327
               :|:          .||                                            |.
Mouse   872 QQFQGQQSQHDHKMTDNDPHTTSTVSTSAEDSQSTEVNMSVPKKMCKRPCILILDSLKAASIQNT 936

  Fly   328 MRALVKYLQMESEDKLGLCLDTSEFRIED-AQNVPQQDNMNDCGVFVCMFAEYLTRDAPITF 388
            ::.|.:||::|.|.|.....:.|:..:.| ...||:|||.:||||::..:.|...:|..:.|
Mouse   937 VQNLREYLEVEWEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNF 998

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:280975	56/240 (23%)
Senp7	NP_079759.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	185..399
		ULP1	<743..1033	CDD:227489	61/259 (24%)
		Protease. /evidence=ECO:0000250	747..1037		60/255 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	873..909		3/35 (9%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810