Protein Alignment CG32110 and SENP2

DIOPT Version :10

• Sequence 1: NP_729837.1
• Gene: CG32110 / 317858
• FlyBaseID: FBgn0052110
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_067640.2
• Gene: SENP2 / 59343
• HGNCID: 23116
• Length: 589
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 100/254 - (39%)
• Similarity: 153/254 - (60%)
• Gaps: 16/254 - (6%)

  Fly   169 ILKQSVHVIED----------IRISSELIPLTKEHHDRLME-LSKYPLQQVIVAKFNLDICGSDI 222
            :|::.|.:||.          .|.:.:|:.||::....:.. |...|..:::.:.|.|.|...||
Human   338 LLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDI 402

  Fly   223 KILTSGGWLNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRLLQSGFDGVKRWTRKVDLFS 287
            :.|.:..||||::|||||||||||::|:  ..|:::..||||.|:|...|:..|||||:.|:||.
Human   403 QTLKNYHWLNDEVINFYMNLLVERNKKQ--GYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFE 465

  Fly   288 MDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQMESEDKLGLCLDTSEF 352
            .::||||:|:. |||.||:|||..|.:.|.:|.|:....:...|::|||.||:.|....|:..|:
Human   466 QEIILVPIHRK-VHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEW 529

  Fly   353 RIEDAQ--NVPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYFRTKMVLELTGDQL 409
            .....:  .:|||.|.:|||:|.|.:|:|::||.||||::..|..||.|||.|:...||
Human   530 THHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:397169	78/171 (46%)
SENP2	NP_067640.2	Nuclear localization signal. /evidence=ECO:0000269|PubMed:16738331	28..31
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:16738331	46..51
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..176
		Nuclear export signal. /evidence=ECO:0000269|PubMed:16738331	317..332
		Peptidase_C48	<336..584	CDD:420019	98/248 (40%)
		Protease. /evidence=ECO:0000269|PubMed:15296745	396..560		73/166 (44%)