DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32110 and Senp17

DIOPT Version :9

Sequence 1:	NP_729837.1	Gene:	CG32110 / 317858	FlyBaseID:	FBgn0052110	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001002833.1	Gene:	Senp17 / 408216	RGDID:	1303080	Length:	475	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	137/468 - (29%)
Similarity:	218/468 - (46%)	Gaps:	104/468 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LAFEK--EIVEKSRYFDLITKECQDYPMAKTMPVLKQPENFQEQEEDVVMAVQEKLKFFRKLTSN 64
            :.|:|  :..:|:|      :|.||..:.|..|...|.:..||:
  Rat    51 MVFQKPGKARKKTR------QEHQDQKLKKEQPGKGQGQKTQEE--------------------- 88

  Fly    65 GPAVPTPLK------VVEKEDIGHKEIPKVVKKVDRKTKLLQAIPAVFKHSHNRRFRRSLF---- 119
            |.....||:      ||||...|.|     .:|  |:..:||..|   :...|.:..|||.
  Rat    89 GSGNIKPLECQPDQTVVEKLAEGGK-----CRK--RQYSVLQEKP---QSPQNEKHARSLEHLQG 143

  Fly   120 ---LRSNYIEQFRRWTDQKNKL---------------NRKRLNEAHQLCLKAKHERIACEIDRYK 166
               :||:.......::|..|..               :|:...|.    |..|.|:...|....:
  Rat   144 GHPVRSDPHRPHPTFSDTSNNKGGMPGHPHGRETAHGDRQPSTEV----LSTKREKRCAEEKCVR 204

  Fly   167 KLILKQSVHVIEDIRI----SSELIP------------LTKEHHDRLMELSKY------------ 203
            ...|:..:...|:..|    ...|:|            |.::.:::..|.:|.
  Rat   205 GNSLEHGLRGTENANILDSGGGRLLPDKVAVVAGEKNALPEQENNQEKEFTKEMEKEVEKALGPG 269

  Fly   204 PLQQVIVAKFNLDICGSDIKILTSGGWLNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRL 268
            ..::::...|.|.|...|::.|.:|.|.||:||||||||||:|:|.:  ..|:::|.||||..:|
  Rat   270 AQEEILSTGFKLKITRGDMQTLKNGQWPNDEIINFYMNLLVQRNENQ--GYPALHAFSTFFYAKL 332

  Fly   269 LQSGFDGVKRWTRKVDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVK 333
            ...|::.||||||.::||..:|||||:||. |||.||:|||..::::|.:|.|:...|:...:..
  Rat   333 KHGGYNSVKRWTRGINLFEKELILVPIHQR-VHWSLVVIDLRKRSIVYLDSMGQTGKNICETIFH 396

  Fly   334 YLQMESEDKLGLCLDTSEFRIED--AQNVPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYF 396
            |||.||:.:..:.||..|::...  :|.:|||.|.:|||:|.|.:|:|::||.|:|||::.|..|
  Rat   397 YLQNESKTRRNMELDPVEWKQYSLTSQEIPQQLNGSDCGMFTCKYADYISRDQPVTFSQQHMPLF 461

  Fly   397 RTKMVLELTGDQL 409
            |.:||.|:....|
  Rat   462 RRRMVWEILHSHL 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:280975	79/171 (46%)
Senp17	NP_001002833.1	Peptidase_C48	<244..470	CDD:304959	90/228 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	189	1.000	Domainoid score	I3195
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3812
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1480705at2759
OrthoFinder	1	1.000	-	-		FOG0000698
OrthoInspector	1	1.000	-	-		mtm8978
orthoMCL	1	0.900	-	-		OOG6_130490
Panther	1	1.100	-	-	O	PTHR12606
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X425
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.970