Protein Alignment CG32110 and SENP1

DIOPT Version :10

• Sequence 1: NP_729837.1
• Gene: CG32110 / 317858
• FlyBaseID: FBgn0052110
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_016874718.1
• Gene: SENP1 / 29843
• HGNCID: 17927
• Length: 707
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 121/393 - (30%)
• Similarity: 202/393 - (51%)
• Gaps: 79/393 - (20%)

  Fly    36 QPENF-----QEQEEDVVMAVQEKLKFFRKLTSNGPAVPTPLKVVEKEDIGHKEIPKVVKKVDRK 95
            ||:|.     |.:..|.|:.::.|          ....|||.....:.::..||:..|
Human   364 QPDNLAASNTQSEGSDSVILLKVK----------DSQTPTPSSTFFQAELWIKELTSV------- 411

  Fly    96 TKLLQAIPAVFKHSHNRRFRRSLFLRSNYIEQFRRWTDQKN---KLNRKRLNEAHQLCLKAKHER 157
                          ::.|.|          |:.|:..:||.   :|..:||.|        :...
Human   412 --------------YDSRAR----------ERLRQIEEQKALALQLQNQRLQE--------REHS 444

  Fly   158 IACEIDRYKKLILKQSV------------HVIEDIRISSELIP-LTKEHHDRLMELSKYPLQ-QV 208
            :...::.:.::.|::.:            |.:.|   |.:..| :|:|....:..:.:...| :|
Human   445 VHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTD---SEDEFPEITEEMEKEIKNVFRNGNQDEV 506

  Fly   209 IVAKFNLDICGSDIKILTSGGWLNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRLLQSGF 273
            :...|.|.|...||:.|....||||:|||||||:|:|||:::  .:|||:|.:|||..:|..:|:
Human   507 LSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEK--GLPSVHAFNTFFFTKLKTAGY 569

  Fly   274 DGVKRWTRKVDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQME 338
            ..|||||:|||:||:|::|||:| :.|||||.::|...|.:.||:|.|..:....|.|::||:.|
Human   570 QAVKRWTKKVDVFSVDILLVPIH-LGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQE 633

  Fly   339 SEDKLGLCLDTSEFRI--EDAQNVPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYFRTKMV 401
            |.||.....||:.:::  :.:|.:|||.|.:|||:|.|.:|:.:|:|.||.|:::.|.|||.:||
Human   634 SIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMV 698

  Fly   402 LEL 404
            .|:
Human   699 WEI 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:397169	80/171 (47%)
SENP1	XP_016874718.1	Peptidase_C48	<483..705	CDD:420019	94/222 (42%)