DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32110 and Senp6

DIOPT Version :9

Sequence 1:	NP_729837.1	Gene:	CG32110 / 317858	FlyBaseID:	FBgn0052110	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001298039.1	Gene:	Senp6 / 215351	MGIID:	1922075	Length:	1139	Species:	Mus musculus

Alignment Length:	337	Identity:	75/337 - (22%)
Similarity:	127/337 - (37%)	Gaps:	111/337 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 LQAIPAVFKHSHNRRFRRSLFLRSNYIEQFRRWTDQKNKLNR-KRLNEAHQLCLKAKHERIACEI 162
            |||||||:         :.|.::....::.:.|.|.|. :|| ..|.|.:.:.:      ....:
Mouse   534 LQAIPAVY---------QKLSMQLQMSKEDKVWNDCKG-INRITSLEEQYIILI------FQTGL 582

  Fly   163 DRYKKLILKQSVHVIEDIRI----------------SSELIPLTKEHHDRL-------------- 197
            |...:::.:.   :|.||.|                :|.|:..|:.:.:.:
Mouse   583 DHQAEVVFES---IITDIGIRNNVPNFFAKILFDEANSRLVACTRSYEESIKGNCAQKENKVKTV 644

  Fly   198 -----------MELSKY---------------PLQQVIV-----AKFNLDICGSDIKILTSGGWL 231
                       .||..:               |::::||     ||..:.:...|:..|:.|.:|
Mouse   645 SFESKIQLRSKQELQFFDDDEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFL 709

  Fly   232 NDKIINFYMNLLV-ERSEKRPGTVPSVYAMSTFFVPRL--------------LQSGFDG-VKRWT 280
            ||.||:||:..|| |:.:|.  ....::..|:||..||              :|....| ||.||
Mouse   710 NDVIIDFYLKYLVLEKLKKE--DADRIHIFSSFFYKRLNQRERRNPETTNLSIQQKRHGRVKTWT 772

  Fly   281 RKVDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQMESED---- 341
            |.||:|..|.|.||::: ..||.|.::..|......|..    :|:.....|......:||
Mouse   773 RHVDIFEKDFIFVPLNE-AAHWFLAVVCFPGLEKPKYEP----NPHYHENAVMQKTPSAEDSCVS 832

  Fly   342 ---KLGLCLDTS 350
               ::|.|...|
Mouse   833 SASEMGACSQNS 844

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:280975	42/144 (29%)
Senp6	NP_001298039.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..51
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	334..395
		Protease	693..1139		45/159 (28%)
		Peptidase_C48	707..>819	CDD:304959	36/118 (31%)
		Peptidase_C48	<999..1075	CDD:304959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810