DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32110 and SENP5

DIOPT Version :9

Sequence 1:	NP_729837.1	Gene:	CG32110 / 317858	FlyBaseID:	FBgn0052110	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_689912.2	Gene:	SENP5 / 205564	HGNCID:	28407	Length:	755	Species:	Homo sapiens

Alignment Length:	298	Identity:	90/298 - (30%)
Similarity:	149/298 - (50%)	Gaps:	55/298 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 EAHQLC--LK-------AKHERIACEIDRYKKLILKQSVHVIEDIRISSELIPLT-KEHHDRL-- 197
            ||..:|  ||       .|:.:.|..:|. ::|.:..|..:.|.::....|:||: ||...||
Human   468 EAPLVCSGLKLENQVGGGKNSQKASPVDD-EQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKD 531

  Fly   198 --------------MELSKYPLQ------QVIVAKFNLDICGSDIKILTSGGWLNDKIINFYMNL 242
                          .|::.|..:      ::...|..||:  .|:..|....||||::||.|..|
Human   532 VFNEDFSNRKPFINREITNYRARHQKCNFRIFYNKHMLDM--DDLATLDGQNWLNDQVINMYGEL 594

  Fly   243 LVERSEKRPGTVP-SVYAMSTFFVPRLLQSGFDGVKRWTRKVDLFSMDLILVPVHQMLVHWCLVI 306
            :::       .|| .|:..::||..:|:..|::||||||:|||||...|:|:|:| :.|||.|:.
Human   595 IMD-------AVPDKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIH-LEVHWSLIT 651

  Fly   307 IDLPAKTMLYYNSRGRGDPNLMRALVKYLQMESEDKLGLCLDTSEFRIEDAQN-----VPQQDNM 366
            :.|..:.:.:|:|:|......:..:.|||..|:.:|     :..|| ::..|.     :|||.|.
Human   652 VTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREK-----NRPEF-LQGWQTAVTKCIPQQKND 710

  Fly   367 NDCGVFVCMFAEYLTRDAPITFSKKDMKYFRTKMVLEL 404
            :||||||..:.:.|..:.|..||::||...|.::..||
Human   711 SDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKEL 748

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:280975	63/175 (36%)
SENP5	NP_689912.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	268..321
		Protease	567..724		60/172 (35%)
		Peptidase_C48	581..753	CDD:280975	65/182 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1480705at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12606
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850