DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha16-3 and ATP6V0C

DIOPT Version :9

Sequence 1:	NP_001189086.1	Gene:	Vha16-3 / 317846	FlyBaseID:	FBgn0028667	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_001185498.1	Gene:	ATP6V0C / 527	HGNCID:	855	Length:	155	Species:	Homo sapiens

Alignment Length:	151	Identity:	120/151 - (79%)
Similarity:	134/151 - (88%)	Gaps:	0/151 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KDKPAYSFFFGSMGAASAIIFSALGAAYGTAKSGTGIAAMAVMRPELIMKSIIPVVMAGIIAIYG 72
            |..|.|:.||..|||::|::||||||||||||||||||||:|||||.||||||||||||||||||
Human     5 KSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYG 69

  Fly    73 LVVSVLIAGSLSDSYTIRKGYIHLAAGLSVGFAGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILI 137
            |||:||||.||:|..::.|.::.|.||||||.:||||||||||||||||||||||||||||||||
Human    70 LVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILI 134

  Fly   138 LIFAEVLGLYGLIVAIYLYTK 158
            |||||||||||||||:.|.||
Human   135 LIFAEVLGLYGLIVALILSTK 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha16-3	NP_001189086.1	V_ATP_synt_C	16..121	CDD:130170	81/104 (78%)
Vha16-3	NP_001189086.1	ATP-synt_Vo_c_ATP6C_rpt2	91..156	CDD:349416	55/64 (86%)
ATP6V0C	NP_001185498.1	V_ATP_synt_C	13..118	CDD:130170	81/104 (78%)
ATP6V0C	NP_001185498.1	ATP-synt_Vo_c_ATP6C_rpt2	86..153	CDD:349416	55/66 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143868
Domainoid	1	1.000	109	1.000	Domainoid score	I6366
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68199
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3429
Isobase	1	0.950	-	0	Normalized mean entropy	S170
OMA	1	1.010	-	-		QHG53914
OrthoDB	1	1.010	-	-		D1534092at2759
OrthoFinder	1	1.000	-	-		FOG0001101
OrthoInspector	1	1.000	-	-		otm40490
orthoMCL	1	0.900	-	-		OOG6_100711
Panther	1	1.100	-	-	O	PTHR10263
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X666
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.760